PAICS and ZMYM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PAICS	ZMYM2
Description		phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase	zinc finger MYM-type containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Extracellular Exosome	Cytosol PML Body
	Molecular Function	Phosphoribosylaminoimidazole Carboxylase Activity Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity Protein Binding ATP Binding Identical Protein Binding 5-amino-4-imidazole Carboxylate Lyase Activity Cadherin Binding	Protein Binding Zinc Ion Binding Ubiquitin Conjugating Enzyme Binding
	Biological Process	'de Novo' IMP Biosynthetic Process Purine Nucleobase Biosynthetic Process	Biological_process
Pathways		Purine ribonucleoside monophosphate biosynthesis	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins
Drugs		Aspartic acid
Diseases
GWAS			Adult body size ( 32376654) Facial emotion recognition (happy faces) ( 28608620) Hand grip strength ( 29691431)
Interacting Genes		21 interacting genes: CDC37 CEP76 CHD3 FXR1 FXR2 L3MBTL2 LNX1 MOB4 NIF3L1 NUDT18 PIAS2 PILRA PRKAG1 PTPRC RAD54L2 RNF4 SMARCD1 TERF1 UBE2I UBE3A ZMYM2	26 interacting genes: CEBPE CREB1 CREBBP FBXL17 FUS GMCL1 HNRNPA2B1 HNRNPH3 IKZF3 PAICS PTBP1 RCOR1 SFPQ SKIL SMAD3 SMAD4 SNIP1 SREBF2 SUMO1 SUMO2 TSC22D2 UBE2A UBE2I UBTF ZBTB3 ZNF512B
Entrez ID		10606	7750
HPRD ID		01401	03745
Ensembl ID		ENSG00000128050	ENSG00000121741
Uniprot IDs		P22234	A0A024RDS3 A8K126 Q9UBW7
PDB IDs		2H31 6YB8 6YB9
Enriched GO Terms of Interacting Partners?
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