NHLRC4 and HSF4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NHLRC4	HSF4
Description		NHL repeat containing 4	heat shock transcription factor 4
Image		No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Nuclear Speck
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Identical Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein K48-linked Ubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Visual Perception Positive Regulation Of Cell Population Proliferation Histone H3-K9 Demethylation Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cell Development Lens Fiber Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin concentration ( 27863252)
Interacting Genes		20 interacting genes: CERK DDIT4L DMRT3 DTX2 ENKD1 HSF4 IGFN1 KRTAP13-2 KRTAP15-1 KRTAP26-1 MGAT5B MYLIP OTX1 PATZ1 PITX1 POGZ POU4F3 PRKAB2 SPAG8 TLX3	46 interacting genes: AKAP8L ALKBH4 BBS2 C10orf55 C19orf54 CDK2AP2 CNOT1 DAXX DUSP26 FAM168B FOXH1 FOXI1 GFOD1 HGS INTS11 KRT31 KRT37 KRT38 KRT40 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP6-2 MAPK1 MAPK14 MAPK3 MAPK8 MKRN3 NHLRC4 NUDT21 NUP62 OIP5 PIH1D2 PITX1 PLA2G10 PPFIBP2 SESTD1 SLC27A5 SMARCA4 SOX10 STOML2 TPM3 UFSP1 YTHDF1 ZBED8 ZMYND12
Entrez ID		283948	3299
HPRD ID		11681	03896
Ensembl ID		ENSG00000257108	ENSG00000102878
Uniprot IDs		P0CG21	A0A024R6X7 Q9ULV5
PDB IDs			6J6V 6J6W
Enriched GO Terms of Interacting Partners?
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