HSF4 and AKAP8L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HSF4	AKAP8L
Description		heat shock transcription factor 4	A-kinase anchoring protein 8 like
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nuclear Speck	Chromatin Nucleus Cytoplasm Nuclear Matrix PML Body Nuclear Speck Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Identical Protein Binding Sequence-specific Double-stranded DNA Binding	DNA Binding RNA Binding Protein Binding Lamin Binding DEAD/H-box RNA Helicase Binding Protein Kinase A Regulatory Subunit Binding Histone Deacetylase Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Visual Perception Positive Regulation Of Cell Population Proliferation Histone H3-K9 Demethylation Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cell Development Lens Fiber Cell Differentiation	MRNA Processing Mitotic Chromosome Condensation RNA Splicing Regulation Of MRNA Export From Nucleus Positive Regulation Of Histone Deacetylation Regulation Of Histone Phosphorylation Cell Cycle G2/M Phase Transition Positive Regulation Of Transcription By RNA Polymerase II Nuclear Membrane Disassembly
Pathways
Drugs
Diseases
GWAS			Red blood cell count ( 32888494)
Interacting Genes		46 interacting genes: AKAP8L ALKBH4 BBS2 C10orf55 C19orf54 CDK2AP2 CNOT1 DAXX DUSP26 FAM168B FOXH1 FOXI1 GFOD1 HGS INTS11 KRT31 KRT37 KRT38 KRT40 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP6-2 MAPK1 MAPK14 MAPK3 MAPK8 MKRN3 NHLRC4 NUDT21 NUP62 OIP5 PIH1D2 PITX1 PLA2G10 PPFIBP2 SESTD1 SLC27A5 SMARCA4 SOX10 STOML2 TPM3 UFSP1 YTHDF1 ZBED8 ZMYND12	67 interacting genes: ABI2 ACTN2 AP1M1 ASF1B ATPAF2 BEX3 BRME1 CARHSP1 CATSPER1 CCDC120 CCDC24 CDC6 CNNM3 CREB5 CSTF2 CSTF2T DGCR6 DHX9 DMRT3 EMD ENKD1 EPHX3 FAM214B FOXD4 GPANK1 GPS2 HEMK1 HGS HSF4 ICAM4 IL18R1 INCA1 KPRP LAGE3 LBR MYOZ1 MYPOP OR7A17 PATZ1 PCDHB14 PEF1 PITX1 PLEKHN1 PPP1R32 PRKAA2 PRKACA PRPF40A RAMAC RASAL3 RTP5 RUSC1 SAMD4A SAXO1 SH3RF2 SNRPC TEKT4 TEKT5 TENT5B TFAP2D TIAL1 TLE5 TMPO TMSB4X TRIB3 TSGA10IP WDR25 ZNF366
Entrez ID		3299	26993
HPRD ID		03896	10641
Ensembl ID		ENSG00000102878	ENSG00000011243
Uniprot IDs		A0A024R6X7 Q9ULV5	Q9ULX6
PDB IDs		6J6V 6J6W
Enriched GO Terms of Interacting Partners?
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