HSF4 and DUSP26

Number of citations of the paper that reports this interaction (PubMedID 16581800)
26

Data Source:
BioGRID (two hybrid, pull down, affinity chromatography technology)
HPRD (in vitro, in vivo, two hybrid)

		HSF4	DUSP26
Description		heat shock transcription factor 4	dual specificity phosphatase 26
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nuclear Speck	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Identical Protein Binding Sequence-specific Double-stranded DNA Binding	P53 Binding Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity MAP Kinase Phosphatase Activity L-phosphoserine Phosphatase Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Visual Perception Positive Regulation Of Cell Population Proliferation Histone H3-K9 Demethylation Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cell Development Lens Fiber Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Negative Regulation Of MAPK Cascade Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Positive Regulation Of Cell Adhesion Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Peptidyl-serine Dephosphorylation
Pathways
Drugs
Diseases
GWAS			Body mass index ( 28892062 25673413) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Metabolite levels ( 23823483) Morning person ( 30696823) Reading disability ( 32108986) Self-reported risk-taking behaviour ( 30271922)
Interacting Genes		46 interacting genes: AKAP8L ALKBH4 BBS2 C10orf55 C19orf54 CDK2AP2 CNOT1 DAXX DUSP26 FAM168B FOXH1 FOXI1 GFOD1 HGS INTS11 KRT31 KRT37 KRT38 KRT40 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP6-2 MAPK1 MAPK14 MAPK3 MAPK8 MKRN3 NHLRC4 NUDT21 NUP62 OIP5 PIH1D2 PITX1 PLA2G10 PPFIBP2 SESTD1 SLC27A5 SMARCA4 SOX10 STOML2 TPM3 UFSP1 YTHDF1 ZBED8 ZMYND12	11 interacting genes: CALCOCO2 CARD10 EPHA2 EPHA7 GOLGA6L9 GRIPAP1 HSF4 IGF1R KRT27 PTK7 RET
Entrez ID		3299	78986
HPRD ID		03896	14421
Ensembl ID		ENSG00000102878	ENSG00000133878
Uniprot IDs		A0A024R6X7 Q9ULV5	Q9BV47
PDB IDs		6J6V 6J6W	2E0T 4B04 4HRF 5GTJ
Enriched GO Terms of Interacting Partners?
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