DKK4 and TSPO2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DKK4	TSPO2
Description		dickkopf WNT signaling pathway inhibitor 4	translocator protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Extracellular Space	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Organelle Membrane
	Molecular Function	Molecular_function Protein Binding Co-receptor Binding Receptor Antagonist Activity	Protein Binding Cholesterol Binding
	Biological Process	Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Hair Follicle Placode Formation Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signaling Receptor Activity	Intracellular Cholesterol Transport Lipid Droplet Organization Enucleate Erythrocyte Differentiation Amino Acid Import Across Plasma Membrane Import Across Plasma Membrane
Pathways		TCF dependent signaling in response to WNT Negative regulation of TCF-dependent signaling by WNT ligand antagonists Signaling by LRP5 mutants
Drugs
Diseases
GWAS			Gastric cancer ( 26129866) Non-cardia gastric cancer ( 26129866)
Interacting Genes		4 interacting genes: GIMAP5 ITGAM NRG1 TSPO2	59 interacting genes: AHNAK2 AQP6 ARL13B ASGR2 ASZ1 BIK CD53 CD69 CD79A CERS4 CLDN4 CNR2 COL4A5 CPLX4 CREB3L1 DKK4 EBP EFNA5 EMP1 ERGIC3 ERP29 FCER1G FCGR1A FFAR2 FNDC9 FXYD3 GGT7 GJB5 GPR152 GPR42 IGFBP5 KCNJ6 KLRC1 LRRC59 MAL MARCHF2 MFF MFSD6 MS4A1 PDZK1IP1 PLEKHO1 PSCA RELL2 RETREG3 RPRM RSPH9 SLC10A1 SLC10A6 SLC16A2 SLC34A2 SLC41A3 SLC7A1 SPAG4 STOM SYT2 TMEM140 TMEM54 TMEM80 VSIR
Entrez ID		27121	222642
HPRD ID		05660	16569
Ensembl ID		ENSG00000104371	ENSG00000112212
Uniprot IDs		Q9UBT3	Q5TGU0
PDB IDs		5O57
Enriched GO Terms of Interacting Partners?
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