DKK4 and GIMAP5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DKK4	GIMAP5
Description		dickkopf WNT signaling pathway inhibitor 4	GTPase, IMAP family member 5
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Extracellular Space	Lysosomal Membrane Integral Component Of Membrane Multivesicular Body Membrane
	Molecular Function	Molecular_function Protein Binding Co-receptor Binding Receptor Antagonist Activity	Protein Binding GTP Binding
	Biological Process	Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Hair Follicle Placode Formation Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signaling Receptor Activity
Pathways		TCF dependent signaling in response to WNT Negative regulation of TCF-dependent signaling by WNT ligand antagonists Signaling by LRP5 mutants
Drugs
Diseases
GWAS
Interacting Genes		4 interacting genes: GIMAP5 ITGAM NRG1 TSPO2	65 interacting genes: ADGRG3 APP AQP3 AQP6 ARL13B BTNL9 CD33 CD53 CHPF2 CLDN7 CREB3L1 CYB561 CYBRD1 DKK4 EBP EDA EDA2R ELOVL4 EMP1 ERGIC3 EVI2B FAM174A FAM210B FATE1 FCER1G GJA8 GJB3 GORAB GRAMD2B IFNGR2 JAGN1 KASH5 KIR3DL3 LAYN LDLRAD1 LSMEM2 M6PR MGST2 MGST3 MILR1 MS4A14 PDZK1IP1 PTGES RETREG3 RNASEK RNF19B SCN3B SHISAL1 SLC10A1 SLC35C2 SMIM3 SPACA1 STOM STX1A STX2 STX4 SYT1 TM4SF18 TM4SF19 TMEM31 TMX1 TMX2 TNFRSF19 TSPAN18 ZFYVE27
Entrez ID		27121	55340
HPRD ID		05660	16280
Ensembl ID		ENSG00000104371	ENSG00000196329
Uniprot IDs		Q9UBT3	A0A090N8P9 Q96F15
PDB IDs		5O57
Enriched GO Terms of Interacting Partners?
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