TSPO2 and ASGR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TSPO2	ASGR2
Description		translocator protein 2	asialoglycoprotein receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Organelle Membrane	Plasma Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Cholesterol Binding	Asialoglycoprotein Receptor Activity Protein Binding Carbohydrate Binding
	Biological Process	Intracellular Cholesterol Transport Lipid Droplet Organization Enucleate Erythrocyte Differentiation Amino Acid Import Across Plasma Membrane Import Across Plasma Membrane	Endocytosis Cell Surface Receptor Signaling Pathway Glycoprotein Metabolic Process Bone Mineralization Regulation Of Protein Stability Lipid Homeostasis
Pathways			Asparagine N-linked glycosylation
Drugs			Antihemophilic factor, human recombinant Lonoctocog alfa Moroctocog alfa
Diseases
GWAS		Gastric cancer ( 26129866) Non-cardia gastric cancer ( 26129866)	Blood protein levels ( 29875488) Congenital heart disease (maternal effect) ( 28468790) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Liver enzyme levels (alkaline phosphatase) ( 33972514) Total cholesterol levels ( 30275531)
Interacting Genes		59 interacting genes: AHNAK2 AQP6 ARL13B ASGR2 ASZ1 BIK CD53 CD69 CD79A CERS4 CLDN4 CNR2 COL4A5 CPLX4 CREB3L1 DKK4 EBP EFNA5 EMP1 ERGIC3 ERP29 FCER1G FCGR1A FFAR2 FNDC9 FXYD3 GGT7 GJB5 GPR152 GPR42 IGFBP5 KCNJ6 KLRC1 LRRC59 MAL MARCHF2 MFF MFSD6 MS4A1 PDZK1IP1 PLEKHO1 PSCA RELL2 RETREG3 RPRM RSPH9 SLC10A1 SLC10A6 SLC16A2 SLC34A2 SLC41A3 SLC7A1 SPAG4 STOM SYT2 TMEM140 TMEM54 TMEM80 VSIR	51 interacting genes: ADAM33 ADIPOQ AIG1 ASGR1 ATP6V0C BET1 CD53 CERS2 CLEC17A CLEC7A CTNNB1 EMP1 F8 FA2H FATE1 GLP1R GLUD1 HES1 HMOX2 HNF1B IL1RL1 LAT LNPEP MCEMP1 MMD2 MROH5 MS4A13 NRG1 ORMDL1 PLN PLP2 PMP22 RPRM SEC22A SLC35A1 SLC35B2 SMIM3 STX8 TFRC TMEM140 TMEM60 TMEM86B TMPPE TRAM1L1 TSPO2 UBIAD1 UPK2 VAMP5 VKORC1 VTI1B YIPF1
Entrez ID		222642	433
HPRD ID		16569	00152
Ensembl ID		ENSG00000112212	ENSG00000161944
Uniprot IDs		Q5TGU0	P07307 Q7Z4G9
PDB IDs
Enriched GO Terms of Interacting Partners?
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