SPAG8 and DMRT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SPAG8	DMRT3
Description		sperm associated antigen 8	doublesex and mab-3 related transcription factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Cytoplasm Spindle Membrane	Chromatin Nucleus
	Molecular Function	Molecular_function Protein Binding Microtubule Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cell Cycle Spermatogenesis Single Fertilization Biological_process Cell Differentiation Positive Regulation Of Protein Binding Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Sex Differentiation Adult Walking Behavior Transmission Of Nerve Impulse Ventral Spinal Cord Interneuron Specification Regulation Of Odontogenesis Of Dentin-containing Tooth Male Sex Differentiation
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545)	Dupuytren's disease ( 28886342) Major depressive disorder ( 23377640) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Response to Homoharringtonine (cytotoxicity) ( 25628645)
Interacting Genes		88 interacting genes: ARMC5 B9D2 BATF2 C19orf54 CARM1 CCDC120 CCNC CDC23 CFP CSTF2 CSTF2T CTAG1A CTAG1B DMRT3 DOK3 DTX2 DYNLL2 EGFL7 FAM168B GIGYF1 GLYCTK GPSM3 HR INCA1 INTS11 JMJD4 KDM3B KLHL32 KRT34 KRTAP10-8 KRTAP11-1 KRTAP13-3 KRTAP15-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP26-1 KRTAP3-1 KRTAP6-2 KRTAP7-1 LASP1 MEOX1 METTL15 MGAT5B NEDD4L NHLRC4 NSD3 NUDT21 PATZ1 PEF1 PFDN5 PHF1 PITX1 PLA2G10 PRMT1 PRMT2 PRMT5 PRR35 RAN RBP3 RIPK4 RNF125 RUSC1 SERGEF SIGMAR1 SMUG1 SMYD1 SNRPB SNRPC SYNGAP1 TEKT3 TEKT5 TENT5B TRIB3 TRIM42 TSC1 TTC23 UBAP2 UBQLN1 UBQLN4 USP2 VPS37C YPEL3 ZBTB32 ZIC1 ZNF34 ZNF581	86 interacting genes: AKAP8L ASPG ATN1 ATP6V0D1 C11orf1 CCNDBP1 CYSRT1 FHL3 FHL5 FOXN1 FRS3 GPSM1 GRN HSF2BP INCA1 KHDRBS3 KPRP KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP19-5 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-3 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 LASP1 LMO2 MDFI MEOX2 MGAT5B MID2 MTUS2 MYOZ3 NBPF19 NFKBID NHLRC4 NOTCH2NLA OIP5 PFDN5 PLEKHF2 PLSCR1 PRDM14 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 PSME3 RBPMS REL RFX6 RUSC1 SAT1 SPAG8 TCF4 TLE5 TRAF1 TRIM23 TRIM27 TRIP6 TSC1 TTC19 UBASH3B USP54 WWOX YPEL3 ZFY ZMYND12 ZNF438
Entrez ID		26206	58524
HPRD ID		12039	16827
Ensembl ID		ENSG00000137098	ENSG00000064218
Uniprot IDs		A0A140VJV0 Q99932	Q9NQL9
PDB IDs
Enriched GO Terms of Interacting Partners?
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