GAST and CYB5R3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GAST	CYB5R3
Description		gastrin	cytochrome b5 reductase 3
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen Nitric-oxide Synthase Complex
	Molecular Function	Hormone Activity Protein Binding	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding Nitrite Reductase (NO-forming) Activity NAD Binding FAD Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Response To Food	Cholesterol Biosynthetic Process Nitric Oxide Biosynthetic Process Blood Circulation
Pathways		G alpha (q) signalling events Gastrin-CREB signalling pathway via PKC and MAPK	Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs		Oxetacaine	NADH Flavin adenine dinucleotide Copper
Diseases
GWAS			Initial pursuit acceleration ( 29064472)
Interacting Genes		24 interacting genes: AQP6 AQP9 ASPH BCL2L13 CISD2 CP CPE CREB3L1 CYB5R3 ERGIC3 FAM209A GOLM1 GPR152 KIR2DL3 KRT34 LHFPL2 MEP1B MMD MME MUC1 PDZK1IP1 PLP1 SLC10A1 TMEM52B	68 interacting genes: ADAM33 AGTRAP AIG1 ALG8 AQP6 ARSA ASGR1 BNIP2 CDIPT CERS4 CNIH1 COL8A2 CSGALNACT2 CYB5A CYCS ELOVL4 FAM210B FAM3C FAXDC2 FUNDC2 FXYD3 GAS1 GAST GPR152 GRM2 HBG2 HSD17B13 L3MBTL2 LAPTM5 LRCH4 MFSD6 NINJ1 NRM NSG1 NXPE3 ORMDL2 PNLIPRP1 REEP4 RPS6KB1 SBF1 SLC10A1 SLC10A6 SLC13A3 SLC22A2 SLC35A4 SLC35B2 SLC38A7 SPP1 STOM TMEM115 TMEM14B TMEM14C TMEM201 TMEM31 TMEM51 TMEM60 TMEM79 TNF TNFRSF10C TUBGCP6 UBIAD1 VAMP1 VAMP4 VAMP5 VMP1 WFDC2 XPNPEP3 ZDHHC15
Entrez ID		2520	1727
HPRD ID		00671	08942
Ensembl ID		ENSG00000184502	ENSG00000100243
Uniprot IDs		A0A0E3VY36 P01350	P00387
PDB IDs		5WRJ	1M91 1UMK
Enriched GO Terms of Interacting Partners?
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