CYB5R3 and NRM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CYB5R3	NRM
Description		cytochrome b5 reductase 3	nurim
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen Nitric-oxide Synthase Complex	Nuclear Envelope Nuclear Inner Membrane Membrane Integral Component Of Membrane Nuclear Membrane
	Molecular Function	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding Nitrite Reductase (NO-forming) Activity NAD Binding FAD Binding	Molecular_function Protein Binding
	Biological Process	Cholesterol Biosynthetic Process Nitric Oxide Biosynthetic Process Blood Circulation	Biological_process
Pathways		Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs		NADH Flavin adenine dinucleotide Copper
Diseases
GWAS		Initial pursuit acceleration ( 29064472)	Alcohol dependence symptom count ( 27151647) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Height ( 31217584) Itch intensity from mosquito bite ( 28199695) Number of sexual partners ( 30643258)
Interacting Genes		68 interacting genes: ADAM33 AGTRAP AIG1 ALG8 AQP6 ARSA ASGR1 BNIP2 CDIPT CERS4 CNIH1 COL8A2 CSGALNACT2 CYB5A CYCS ELOVL4 FAM210B FAM3C FAXDC2 FUNDC2 FXYD3 GAS1 GAST GPR152 GRM2 HBG2 HSD17B13 L3MBTL2 LAPTM5 LRCH4 MFSD6 NINJ1 NRM NSG1 NXPE3 ORMDL2 PNLIPRP1 REEP4 RPS6KB1 SBF1 SLC10A1 SLC10A6 SLC13A3 SLC22A2 SLC35A4 SLC35B2 SLC38A7 SPP1 STOM TMEM115 TMEM14B TMEM14C TMEM201 TMEM31 TMEM51 TMEM60 TMEM79 TNF TNFRSF10C TUBGCP6 UBIAD1 VAMP1 VAMP4 VAMP5 VMP1 WFDC2 XPNPEP3 ZDHHC15	50 interacting genes: AGR3 ANK1 AQP6 ARL13B ATP6V0B BIK CLRN1 CNR2 CPLX4 CREB3L1 CYB5R3 CYBC1 ERGIC3 ERP29 FAM209A FCER1G FFAR2 FRMD3 GOLT1A GORAB GPR151 GPR42 GPX8 HDAC11 HHLA2 HSD17B13 KIR2DL3 MFF MGST3 MRM1 OPN1LW PARP15 PEX12 RETREG3 RHBDD2 RMDN3 RNASEH1 SAR1A SLC10A2 SLC10A6 SLC18A1 SLC30A2 SLC35C2 SPAG4 SSMEM1 STX1A SUN2 TMEM52B TMX2 TRIM59
Entrez ID		1727	11270
HPRD ID		08942	10120
Ensembl ID		ENSG00000100243	ENSG00000137404
Uniprot IDs		P00387	A0A1U9X845 B3KQU6 Q8IXM6
PDB IDs		1M91 1UMK
Enriched GO Terms of Interacting Partners?
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