CYB5R3 and SLC35B2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CYB5R3	SLC35B2
Description		cytochrome b5 reductase 3	solute carrier family 35 member B2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen Nitric-oxide Synthase Complex	Golgi Membrane Golgi Apparatus Membrane Integral Component Of Membrane Integral Component Of Golgi Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding Nitrite Reductase (NO-forming) Activity NAD Binding FAD Binding	Protein Binding Transmembrane Transporter Activity 3'-phosphoadenosine 5'-phosphosulfate Transmembrane Transporter Activity
	Biological Process	Cholesterol Biosynthetic Process Nitric Oxide Biosynthetic Process Blood Circulation	Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling 3'-phosphoadenosine 5'-phosphosulfate Transport 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process 3'-phospho-5'-adenylyl Sulfate Transmembrane Transport
Pathways		Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation	Transport and synthesis of PAPS Transport of nucleotide sugars
Drugs		NADH Flavin adenine dinucleotide Copper
Diseases
GWAS		Initial pursuit acceleration ( 29064472)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		68 interacting genes: ADAM33 AGTRAP AIG1 ALG8 AQP6 ARSA ASGR1 BNIP2 CDIPT CERS4 CNIH1 COL8A2 CSGALNACT2 CYB5A CYCS ELOVL4 FAM210B FAM3C FAXDC2 FUNDC2 FXYD3 GAS1 GAST GPR152 GRM2 HBG2 HSD17B13 L3MBTL2 LAPTM5 LRCH4 MFSD6 NINJ1 NRM NSG1 NXPE3 ORMDL2 PNLIPRP1 REEP4 RPS6KB1 SBF1 SLC10A1 SLC10A6 SLC13A3 SLC22A2 SLC35A4 SLC35B2 SLC38A7 SPP1 STOM TMEM115 TMEM14B TMEM14C TMEM201 TMEM31 TMEM51 TMEM60 TMEM79 TNF TNFRSF10C TUBGCP6 UBIAD1 VAMP1 VAMP4 VAMP5 VMP1 WFDC2 XPNPEP3 ZDHHC15	14 interacting genes: AQP6 ASGR2 CD69 CLDN15 CREB3L1 CYB5R3 ERGIC3 GOLM1 LMNA RNF170 SHISAL1 TEX29 TMEM237 TMEM248
Entrez ID		1727	347734
HPRD ID		08942	11576
Ensembl ID		ENSG00000100243	ENSG00000157593
Uniprot IDs		P00387	Q8TB61
PDB IDs		1M91 1UMK
Enriched GO Terms of Interacting Partners?
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