ATP13A2 and MYCBP2

Number of citations of the paper that reports this interaction (PubMedID 22645275)
28

Data Source:
BioGRID (two hybrid)

		ATP13A2	MYCBP2
Description		ATPase cation transporting 13A2	MYC binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Lysosome Lysosomal Membrane Late Endosome Multivesicular Body Autophagosome Integral Component Of Membrane Transport Vesicle Late Endosome Membrane Vesicle Multivesicular Body Membrane Neuron Projection Neuronal Cell Body Lysosomal Lumen Integral Component Of Lysosomal Membrane	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Membrane Axon Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding ATP Binding Zinc Ion Binding ABC-type Polyamine Transporter Activity ATP Hydrolysis Activity ATPase-coupled Cation Transmembrane Transporter Activity Manganese Ion Binding Phosphatidic Acid Binding Phosphatidylinositol-3,5-bisphosphate Binding Cupric Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Small GTPase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cellular Calcium Ion Homeostasis Cellular Iron Ion Homeostasis Cellular Zinc Ion Homeostasis Autophagy Lysosomal Transport Positive Regulation Of Gene Expression Regulation Of Mitochondrion Organization Regulation Of Macroautophagy Regulation Of Autophagosome Size Cellular Cation Homeostasis Regulation Of Intracellular Protein Transport Ion Transmembrane Transport Cellular Response To Oxidative Stress Protein Autophosphorylation Positive Regulation Of Protein Secretion Regulation Of Endopeptidase Activity Zinc Ion Homeostasis Lipid Homeostasis Protein Localization To Lysosome Autophagosome-lysosome Fusion Cellular Response To Manganese Ion Cellular Response To Zinc Ion Extracellular Exosome Biogenesis Regulation Of Protein Localization To Nucleus Negative Regulation Of Neuron Death Polyamine Transmembrane Transport Regulation Of Autophagy Of Mitochondrion Positive Regulation Of Exosomal Secretion Spermine Transmembrane Transport Regulation Of Chaperone-mediated Autophagy Autophagosome Organization Regulation Of Glucosylceramidase Activity Regulation Of Lysosomal Protein Catabolic Process Negative Regulation Of Lysosomal Protein Catabolic Process Peptidyl-aspartic Acid Autophosphorylation Regulation Of Ubiquitin-specific Protease Activity	Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Neuromuscular Process Regulation Of Cytoskeleton Organization Regulation Of Axon Guidance
Pathways		Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 25429064 31562340 20189936) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 28552196 34021172 25673412) Intraocular pressure ( 29617998) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28552196 34021172) Waist-hip index ( 34021172)	Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		36 interacting genes: ACKR3 ATP5MC2 CCKBR CMTM6 COL1A1 CXCR4 CYGB DCAF7 EMC7 F2R FAM111B FAM8A1 FKBP8 FUNDC2 GPR21 HIPK1 ICAM2 LMAN2 LRP6 MEX3B MYCBP2 NPY1R NRXN1 OCA2 OSTC PCDHB10 PCMTD2 PDIA6 PSME3IP1 SEC61B SPCS2 TSPAN14 UBE2J2 VAMP2 WDR5B WDR83OS	52 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 ATP1B3 CALM1 CD81 CDC14B CFL1 COMMD6 CUEDC2 DACH1 DHRS4L2 EDNRB ERBB3 FBXL3 FBXO45 FHL3 FSCN1 HSP90AB1 IGFBP6 LDHB LSM14A MAST3 MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 SCEL SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ
Entrez ID		23400	23077
HPRD ID		13677	10104
Ensembl ID		ENSG00000159363	ENSG00000005810
Uniprot IDs		Q8N4D4 Q8NBS1 Q9NQ11	O75592
PDB IDs			5O6C 6T7F
Enriched GO Terms of Interacting Partners?
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