MYCBP2 and NMNAT2

Number of citations of the paper that reports this interaction (PubMedID 29643511)
50

Data Source:
BioGRID (enzymatic study, affinity chromatography technology)

		MYCBP2	NMNAT2
Description		MYC binding protein 2	nicotinamide nucleotide adenylyltransferase 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Membrane Axon Intracellular Membrane-bounded Organelle	Golgi Membrane Late Endosome Golgi Apparatus Trans-Golgi Network Cytosol Axon Cytoplasmic Vesicle Membrane Synapse
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Small GTPase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Nicotinamide-nucleotide Adenylyltransferase Activity Nicotinate-nucleotide Adenylyltransferase Activity ATP Binding
	Biological Process	Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Neuromuscular Process Regulation Of Cytoskeleton Organization Regulation Of Axon Guidance	Nucleotide Biosynthetic Process NAD Biosynthetic Process
Pathways			Nicotinate metabolism
Drugs
Diseases
GWAS		Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)	Clozapine-induced agranulocytosis ( 25187353) General cognitive ability ( 29844566) Moderate-to-late spontaneous preterm birth ( 31194736) Morning person ( 30696823) Obesity-related traits ( 23251661) Reaction time ( 29844566) Systemic lupus erythematosus ( 28714469) Systemic lupus erythematosus and Systemic sclerosis ( 23740937)
Interacting Genes		52 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 ATP1B3 CALM1 CD81 CDC14B CFL1 COMMD6 CUEDC2 DACH1 DHRS4L2 EDNRB ERBB3 FBXL3 FBXO45 FHL3 FSCN1 HSP90AB1 IGFBP6 LDHB LSM14A MAST3 MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 SCEL SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ	2 interacting genes: APP MYCBP2
Entrez ID		23077	23057
HPRD ID		10104	09786
Ensembl ID		ENSG00000005810	ENSG00000157064
Uniprot IDs		O75592	Q9BZQ4
PDB IDs		5O6C 6T7F
Enriched GO Terms of Interacting Partners?
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