MYCBP2 and SPRYD3

Number of citations of the paper that reports this interaction (PubMedID 21653829)
98

Data Source:
BioGRID (two hybrid)

		MYCBP2	SPRYD3
Description		MYC binding protein 2	SPRY domain containing 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Membrane Axon Intracellular Membrane-bounded Organelle	Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Small GTPase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Neuromuscular Process Regulation Of Cytoskeleton Organization Regulation Of Axon Guidance	Cytoskeleton Organization Cell Surface Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)	Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		52 interacting genes: AATF APPL1 ARL6IP5 ASB8 ATP13A2 ATP1B3 CALM1 CD81 CDC14B CFL1 COMMD6 CUEDC2 DACH1 DHRS4L2 EDNRB ERBB3 FBXL3 FBXO45 FHL3 FSCN1 HSP90AB1 IGFBP6 LDHB LSM14A MAST3 MYC NDUFB9 NMNAT2 OAZ1 PABPN1 PI4KB PRXL2A PTPN12 PUF60 RGPD8 RPS5 SCEL SERPINB6 SOD1 SPARCL1 SPRYD3 SRPK2 TBC1D9 TBC1D9B TBR1 TTN UBE2D2 UBE2D3 UBE2L3 UCHL1 YWHAG YWHAQ	1 interacting genes: MYCBP2
Entrez ID		23077	84926
HPRD ID		10104	08603
Ensembl ID		ENSG00000005810	ENSG00000167778
Uniprot IDs		O75592	A0A024RAX4 Q8NCJ5
PDB IDs		5O6C 6T7F	2YYO
Enriched GO Terms of Interacting Partners?
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