NCSTN and APH1B

  • Number of citations of the paper that reports this interaction (PubMedID 12857757)
  • 74
  • Data Source:
  • HPRD (in vitro, in vivo)

NCSTN

APH1B

Description nicastrin aph-1 homolog B, gamma-secretase subunit
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Post bronchodilator FEV1 in COPD ( 26634245)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Estimated glomerular filtration rate ( 31152163)
  • Family history of Alzheimer's disease ( 30617256)
  • Metabolite levels ( 23823483)
  • Myopia ( 27182965)
  • Refractive error ( 32231278)
  • Response to fenofibrate (triglyceride levels) ( 27002377)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes 12 interacting genes: ABL1 APH1A APH1B APP BACE1 MAPK9 PSEN1 PSEN2 PSENEN PTEN SPP1 TMED10 8 interacting genes: FXYD6-FXYD2 NAB2 NCSTN PSEN1 PSEN2 TM4SF4 TRARG1 VSTM1
Entrez ID 23385 83464
HPRD ID 05584 06361
Ensembl ID ENSG00000162736 ENSG00000138613
Uniprot IDs B4DR82 Q92542 Q8WW43
PDB IDs 2N7Q 2N7R 4UIS 5A63 5FN2 5FN3 5FN4 5FN5 6IDF 6IYC 6LQG 6LR4 7C9I 7D8X
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?