JADE2 and ZNF496

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		JADE2	ZNF496
Description		jade family PHD finger 2	zinc finger protein 496
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome	Nucleus
	Molecular Function	Protein Binding Transferase Activity Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Protein Ubiquitination Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated
Pathways		HATs acetylate histones	Generic Transcription Pathway
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 34211149 27798627) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet distribution width ( 27863252) Smoking cessation ( 33082346) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 28869590) White blood cell count ( 32888494)	Chromium levels ( 26025379) Platelet distribution width ( 32888494)
Interacting Genes		27 interacting genes: C5orf15 CBX8 CDCA7L CSNK2A1 DDX46 FBXO7 FSTL4 GAS2L2 GORASP2 H3-4 ING4 IRAK1 KLK2 MEAF6 PACSIN1 RAPGEF6 SAR1B SASH1 SH2B2 SMAD5-AS1 TCF7 UQCRQ ZBTB3 ZBTB5 ZCCHC10 ZNF417 ZNF496	24 interacting genes: ARR3 CBX3 JADE2 NR3C1 NSD1 PGBD1 POLR3D PPARG RAI1 RNF8 SCAND1 SNIP1 SSX3 SUMO2 SUMO3 SUPT5H TRIM28 ZKSCAN4 ZNF446 ZNF483 ZSCAN12 ZSCAN21 ZSCAN22 ZZZ3
Entrez ID		23338	84838
HPRD ID		15124	15805
Ensembl ID		ENSG00000043143	ENSG00000162714
Uniprot IDs		A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1	Q96IT1
PDB IDs
Enriched GO Terms of Interacting Partners?
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