FLOT2 and MAGEB4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FLOT2	MAGEB4
Description		flotillin 2	MAGE family member B4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Uropod Acrosomal Membrane Endosome Plasma Membrane Caveola Adherens Junction Focal Adhesion Membrane Basolateral Plasma Membrane Apical Plasma Membrane Flotillin Complex Lamellipodium Endocytic Vesicle Cortical Actin Cytoskeleton Cytoplasmic Vesicle Vesicle Dendrite Cytoplasm Intracellular Membrane-bounded Organelle Cell-cell Contact Zone Perinuclear Region Of Cytoplasm Extracellular Exosome Glutamatergic Synapse Anchored Component Of Presynaptic Active Zone Membrane	Nucleus Cytoplasm
	Molecular Function	Protease Binding Protein Binding Ionotropic Glutamate Receptor Binding	Protein Binding
	Biological Process	Membrane Raft Assembly Cell Adhesion Epidermis Development Negative Regulation Of Gene Expression Regulation Of Heterotypic Cell-cell Adhesion Regulation Of Toll-like Receptor 3 Signaling Pathway Protein Localization To Plasma Membrane Raft Regulation Of Myoblast Differentiation Protein Stabilization Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Localization To Plasma Membrane Anterograde Dendritic Transport Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Negative Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Establishment Of T Cell Polarity	Negative Regulation Of Transcription By RNA Polymerase II
Pathways		RIPK1-mediated regulated necrosis Regulation of necroptotic cell death Synaptic adhesion-like molecules RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle RND3 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Declining hemoglobin trajectory in blood donors ( 33491795) Mean corpuscular hemoglobin ( 29403010) Red blood cell count ( 27863252)
Interacting Genes		11 interacting genes: APP CAV1 CAV2 DXO FLOT1 FYN HGS MAGEB4 NMNAT1 SPATA24 UBC	41 interacting genes: AARD ACOT11 ARID3A BLOC1S1 CCDC136 CCDC14 DVL3 EEF1AKMT3 FAM136A FAM166B FERD3L FLOT2 FTSJ3 GOLGA6L2 GPATCH2 H2AP HGS IHO1 KANK2 KRT38 LZTS2 MAGEA8 MED21 MESD NEUROD4 PFDN6 PICK1 PJA1 ROCK1 RUNDC3A SH2D1B THOC1 TNR TRAK1 UQCRB USHBP1 USP25 WDR62 YWHAE ZNF341 ZRANB1
Entrez ID		2319	4115
HPRD ID		00580	02150
Ensembl ID		ENSG00000132589	ENSG00000120289
Uniprot IDs		A0A024QZ62 J3QLD9 Q14254 Q6FG43 Q9BTI6	O15481
PDB IDs
Enriched GO Terms of Interacting Partners?
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