GGA3 and PLEKHB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GGA3	PLEKHB2
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 3	pleckstrin homology domain containing B2
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GO Annotations	Cellular Component	Lysosome Golgi Apparatus Trans-Golgi Network Endosome Membrane Early Endosome Membrane Protein-containing Complex Recycling Endosome Membrane	Integral Component Of Membrane Recycling Endosome Membrane
	Molecular Function	Protein Binding Small GTPase Binding Phosphatidylinositol Binding Ubiquitin Binding Protein-containing Complex Binding	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	Protein Targeting To Lysosome Intracellular Protein Transport Regulation Of Protein Stability Protein Destabilization Endocytic Recycling Protein Localization To Cell Surface Golgi To Plasma Membrane Protein Transport Positive Regulation Of Protein Catabolic Process Negative Regulation Of Amyloid-beta Formation	Regulation Of Cell Differentiation
Pathways		TBC/RABGAPs MET receptor recycling Amyloid fiber formation
Drugs
Diseases
GWAS
Interacting Genes		38 interacting genes: ADRA2A ADRA2B AFTPH AP1S2 ARAP3 ARF1 ARF3 CDKN2A CLINT1 CLTC CYTH2 DAZAP2 EGFR GGA1 GGA2 IGF2R LITAF LRP10 M6PR P4HA3 PACS1 PLEKHB2 RABEP1 RNF11 RNF214 RPS27A STAB1 SYNRG TBC1D3 TOLLIP TRAPPC6A TRIM23 TSG101 UBC UPRT VPS11 VPS18 ZNF497	52 interacting genes: ATF7IP BHLHE40 C1orf94 CD68 CDA CFC1 CLDN19 DAZAP2 DCUN1D1 EMP1 EMP3 EPN1 EPN2 FAM168A FOXD4L3 GGA3 GJB2 GLIS2 GPR45 HEY1 HEYL HGS HIVEP1 MAP3K1 MED25 MTURN NRGN NTAQ1 OTUB2 PIP4P1 PITX1 POGZ PROP1 RHBDD1 RPS27A SFT2D1 SNRPB STAM2 SYNGR1 TAX1BP1 TRARG1 UBA52 UBAC1 UBAP2 UBASH3A UBB UBC UBQLN2 UBXN6 UPF1 YOD1 ZFAND2A
Entrez ID		23163	55041
HPRD ID		10443	15144
Ensembl ID		ENSG00000125447	ENSG00000115762
Uniprot IDs		A8K6M0 B7Z456 Q9NZ52	A0A024QZ35 A0A0A0MSE9 A0A0A0MSI4 B4DJB7 Q96CS7
PDB IDs		1JPL 1JUQ 1LF8 1P4U 1WR6 1YD8	3AJ4 3VIA
Enriched GO Terms of Interacting Partners?
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