ALDOB and TXN2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ALDOB	TXN2
Description		aldolase, fructose-bisphosphate B	thioredoxin 2
Image
GO Annotations	Cellular Component	Microtubule Organizing Center Cytosol Centriolar Satellite Extracellular Exosome	Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body
	Molecular Function	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Identical Protein Binding ATPase Binding Fructose-1-phosphate Aldolase Activity Fructose Binding	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein-disulfide Reductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding
	Biological Process	Fructose Metabolic Process Glycolytic Process NADH Oxidation Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of ATPase Activity Vacuolar Proton-transporting V-type ATPase Complex Assembly	Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Xenobiotic Stimulus Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Cell Redox Homeostasis Response To Axon Injury
Pathways		Hereditary fructose intolerance Glycolysis Gluconeogenesis Fructose catabolism	Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species
Drugs		1,6-Fructose Diphosphate (Linear Form) sn-glycerol 3-phosphate Dihydroxyacetone phosphate
Diseases
GWAS		Age-related cataracts ( 25352737) Liver enzyme levels (alkaline phosphatase) ( 33972514 22001757) Serum alkaline phosphatase levels ( 33547301 29403010 33339817)
Interacting Genes		22 interacting genes: AGXT2 ALDOA APP ATP6V1E1 BMPR1A BUB1 CDKN2A CTNNA1 DCC FLCN HIVEP1 HSPA8 MAP2K4 MCC MLH1 MLH3 MUC20 NRAS SMAD4 SRC STK11 TXN2	80 interacting genes: ABI3 AGTRAP ALDOB ANKRD36B AP2B1 BCAS2 BHLHB9 C11orf49 CCDC197 CDCA4 CEP70 CGGBP1 CHMP1A CIB4 CRACR2B DCTD DDIT3 ETHE1 FAM9B FHL5 FMNL2 GOLGA6L9 GPRASP2 GTPBP2 GUCD1 HAUS1 HAUS8 KAZN KRT18 KRT27 KRT40 LCN2 MAGEA11 MAGEA4 MAGEB2 MAPRE2 MAPRE3 MDFI MEOX2 MIPOL1 MLH1 MRFAP1 MRFAP1L1 MTUS2 MYL9 NUTM1 ODAD1 PEX19 POMC PPCDC PPP1R16B PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SAT1 SCYL3 SHARPIN SPTA1 SSNA1 STN1 STUB1 SUN2 SYCE1 TFIP11 THAP1 TIFA TMOD4 TRIM21 TRIP6 TTC32 UCHL5 UQCC2 VIM VPS52 ZBTB14 ZMYND12 ZSCAN32
Entrez ID		229	25828
HPRD ID		01972	07161
Ensembl ID		ENSG00000136872	ENSG00000100348
Uniprot IDs		A0A024R145 P05062	Q99757
PDB IDs		1QO5 1XDL 1XDM	1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?
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