TXN2 and FMNL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TXN2	FMNL2
Description		thioredoxin 2	formin like 2
Image
GO Annotations	Cellular Component	Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body	Cytosol
	Molecular Function	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein-disulfide Reductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding	Small GTPase Binding Cadherin Binding Actin Filament Binding
	Biological Process	Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Xenobiotic Stimulus Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Cell Redox Homeostasis Response To Axon Injury	Cytoskeleton Organization Regulation Of Cell Shape Cell Migration Regulation Of Cell Morphogenesis Cortical Actin Cytoskeleton Organization
Pathways		Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species	RHO GTPases Activate Formins RHOC GTPase cycle CDC42 GTPase cycle
Drugs
Diseases
GWAS			Asthma (childhood onset) ( 27611488) Corneal astigmatism ( 30306274) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 33627673 29891935) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 29785010 31959993 30054594 29235454) Lymphocyte counts ( 32888494) Refractive astigmatism ( 30306274) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) White blood cell count ( 32888494)
Interacting Genes		80 interacting genes: ABI3 AGTRAP ALDOB ANKRD36B AP2B1 BCAS2 BHLHB9 C11orf49 CCDC197 CDCA4 CEP70 CGGBP1 CHMP1A CIB4 CRACR2B DCTD DDIT3 ETHE1 FAM9B FHL5 FMNL2 GOLGA6L9 GPRASP2 GTPBP2 GUCD1 HAUS1 HAUS8 KAZN KRT18 KRT27 KRT40 LCN2 MAGEA11 MAGEA4 MAGEB2 MAPRE2 MAPRE3 MDFI MEOX2 MIPOL1 MLH1 MRFAP1 MRFAP1L1 MTUS2 MYL9 NUTM1 ODAD1 PEX19 POMC PPCDC PPP1R16B PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SAT1 SCYL3 SHARPIN SPTA1 SSNA1 STN1 STUB1 SUN2 SYCE1 TFIP11 THAP1 TIFA TMOD4 TRIM21 TRIP6 TTC32 UCHL5 UQCC2 VIM VPS52 ZBTB14 ZMYND12 ZSCAN32	13 interacting genes: AP1B1 AP2B1 APP ARL6IP6 CCDC197 CDC42 KRT27 MIPOL1 NECAB1 PNMA1 PRPF40A SUOX TXN2
Entrez ID		25828	114793
HPRD ID		07161	13545
Ensembl ID		ENSG00000100348	ENSG00000157827
Uniprot IDs		Q99757	Q96PY5
PDB IDs		1UVZ 1W4V 1W89	4YC7
Enriched GO Terms of Interacting Partners?
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