TMEM218 and GJB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM218	GJB1
Description		transmembrane protein 218	gap junction protein beta 1
Image		No pdb structure
GO Annotations	Cellular Component	Cilium Integral Component Of Membrane	Endoplasmic Reticulum Membrane Connexin Complex Integral Component Of Membrane Lateral Plasma Membrane
	Molecular Function	Protein Binding	Gap Junction Channel Activity Protein Binding Identical Protein Binding
	Biological Process		Cell-cell Signaling Nervous System Development Purine Ribonucleotide Transport Gap Junction Assembly Transmembrane Transport Epididymis Development
Pathways			Oligomerization of connexins into connexons Oligomerization of connexins into connexons Transport of connexins along the secretory pathway Gap junction assembly
Drugs
Diseases
GWAS		Breast cancer (survival) ( 25890600) Familial lung adenocarcinoma ( 29924316)
Interacting Genes		72 interacting genes: APH1A AQP2 AQP6 ARL13B ASZ1 ATP6V0E1 BSCL2 CD300A CD53 CD79A CLDN2 CLEC10A CLEC17A CPLX4 CREB3L1 CTLA4 DAGLA EBP ELOVL2 ELOVL4 EMP1 ERGIC3 FAM209A FCER1G FRMD3 GDAP1 GJB1 GJB4 GJB6 GPR152 GPR61 GPX8 IFNGR2 KCNJ6 KCNK5 KIR2DL3 LDLRAD1 LHFPL5 LMNA LSMEM2 MFF MS4A3 MTIF3 NPFFR2 PCNA PDCD1LG2 PIK3IP1 PLEKHO1 PSCA RETREG3 SAR1A SDC3 SLC10A4 SLC10A6 SLC18A1 SMIM3 SSMEM1 TM4SF18 TMED8 TMEM106C TMEM182 TMEM207 TMEM234 TMEM31 TMEM45B TMEM52B TMEM88 TMPRSS2 TRHR TSPAN12 TSPAN18 VSIR	57 interacting genes: APOL3 APP BMP10 C1GALT1 C2CD2L C3orf52 CALM1 CD37 CD79A CDIPT CLEC7A CMTM3 CMTM5 CNST COMT CTXN3 CXCL9 EFNA5 EGFR EMP3 EPHA1 GJB2 GLP1R GPR25 IER3IP1 ITGAM LAT LHFPL2 MAL MAL2 MFF MS4A13 MST1R NDUFB11 NIPAL4 PRKACA PRKCA PTPN2 PTPN9 RTP2 SCD SERTM1 SLC12A7 SRC STX8 TEX264 TF TM4SF4 TMEM120B TMEM14C TMEM19 TMEM218 TMEM98 UPK1B VEGFA VKORC1 YIPF6
Entrez ID		219854	2705
HPRD ID		19054	02367
Ensembl ID		ENSG00000150433	ENSG00000169562
Uniprot IDs		A2RU14	A0A654ICJ7 P08034
PDB IDs			1TXH 5KK9
Enriched GO Terms of Interacting Partners?
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