FANCG and TADA2A

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid)

		FANCG	TADA2A
Description		FA complementation group G	transcriptional adaptor 2A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Mitochondrion Cytosol Plasma Membrane Fanconi Anaemia Nuclear Complex	SAGA Complex Nucleus Chromosome SAGA-type Complex
	Molecular Function	Damaged DNA Binding Protein Binding	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding
	Biological Process	Ovarian Follicle Development DNA Repair Cellular Response To DNA Damage Stimulus Mitochondrion Organization Spermatid Development Response To Radiation Interstrand Cross-link Repair	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Acetylation Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated
Pathways		Fanconi Anemia Pathway	HATs acetylate histones
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494)	Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) Monocyte percentage of white cells ( 32888494) Ovarian cancer ( 23535730) Plateletcrit ( 32888494) White blood cell count ( 32888494)
Interacting Genes		44 interacting genes: BRCA2 BRCC3 CAPN1 CBY2 CDK1 COG6 CTBP1 CYP19A1 CYP2E1 DOK5 ERCC4 FANCA FANCC FANCE FANCF FTSJ3 GABPB1 GATA1 GOLGA2 HES1 HGS IHO1 IKZF3 KRT13 KRT19 LNX2 MEOX2 NECAB2 NLGN3 PSMB1 RINT1 RTN2 SAMD3 SSX2IP TADA2A TCEANC TFIP11 TLE5 TPRX1 UIMC1 USHBP1 XRCC3 ZBED1 ZBTB1	49 interacting genes: ARNT2 C1orf109 CCDC116 CCDC134 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FANCG FARS2 FBF1 GPSM3 HGS HNRNPLL KAT2A KLC4 KLHL38 KPNA2 LMO1 MAGOH MAGOHB MCPH1 MFAP1 MKRN3 MTX2 MYC NFE2L2 NOL4L-DT NR3C1 PPP1R16B PRKAB2 PRPF31 QARS1 RNF6 RTL8B SF3A3 TADA3 TCF3 TEKT4 THOC1 TTC23 TTC9C VPS25 ZCCHC12 ZFYVE26 ZNF417 ZNF564 ZNF688
Entrez ID		2189	6871
HPRD ID		04262	03784
Ensembl ID		ENSG00000221829	ENSG00000276234
Uniprot IDs		O15287 Q53XM5	A0A024R0Y4 A0A087WWR4 B3KU13 O75478
PDB IDs			1X41
Enriched GO Terms of Interacting Partners?
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