TADA2A and VPS25

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TADA2A	VPS25
Description		transcriptional adaptor 2A	vacuolar protein sorting 25 homolog
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GO Annotations	Cellular Component	SAGA Complex Nucleus Chromosome SAGA-type Complex	ESCRT II Complex Nucleus Nucleoplasm Cytoplasm Cytosol Endosome Membrane Extracellular Exosome
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding	Structural Molecule Activity Protein Binding Protein Homodimerization Activity Protein N-terminus Binding
	Biological Process	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Acetylation Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Macroautophagy Multivesicular Body Assembly Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Pathways		HATs acetylate histones	Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events
Drugs
Diseases
GWAS		Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) Monocyte percentage of white cells ( 32888494) Ovarian cancer ( 23535730) Plateletcrit ( 32888494) White blood cell count ( 32888494)
Interacting Genes		49 interacting genes: ARNT2 C1orf109 CCDC116 CCDC134 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FANCG FARS2 FBF1 GPSM3 HGS HNRNPLL KAT2A KLC4 KLHL38 KPNA2 LMO1 MAGOH MAGOHB MCPH1 MFAP1 MKRN3 MTX2 MYC NFE2L2 NOL4L-DT NR3C1 PPP1R16B PRKAB2 PRPF31 QARS1 RNF6 RTL8B SF3A3 TADA3 TCF3 TEKT4 THOC1 TTC23 TTC9C VPS25 ZCCHC12 ZFYVE26 ZNF417 ZNF564 ZNF688	22 interacting genes: APIP ASPG B9D2 BEND5 BPIFA1 CHMP6 CRLF3 DCAKD GPR35 LTB4R2 PICK1 REL RHOXF2 SDCBP2 SEPTIN14 SNF8 SPG21 SPRY2 SYCE1 TADA2A TRIM27 VPS36
Entrez ID		6871	84313
HPRD ID		03784	14396
Ensembl ID		ENSG00000276234	ENSG00000131475
Uniprot IDs		A0A024R0Y4 A0A087WWR4 B3KU13 O75478	A0A024R1X3 Q9BRG1
PDB IDs		1X41	2ZME 3CUQ 3HTU
Enriched GO Terms of Interacting Partners?
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