FANCG and XRCC3

Number of citations of the paper that reports this interaction (PubMedID 16621732)
21

Data Source:
HPRD (in vivo, two hybrid)

		FANCG	XRCC3
Description		FA complementation group G	X-ray repair cross complementing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Mitochondrion Cytosol Plasma Membrane Fanconi Anaemia Nuclear Complex	Chromosome, Telomeric Region Nucleus Nucleoplasm Replication Fork Cytoplasm Mitochondrion Cytosol Rad51C-XRCC3 Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Damaged DNA Binding Protein Binding	Four-way Junction DNA Binding Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Crossover Junction Endodeoxyribonuclease Activity
	Biological Process	Ovarian Follicle Development DNA Repair Cellular Response To DNA Damage Stimulus Mitochondrion Organization Spermatid Development Response To Radiation Interstrand Cross-link Repair	Telomere Maintenance Via Recombination Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination Cellular Response To DNA Damage Stimulus Response To Organic Substance Regulation Of Centrosome Duplication Interstrand Cross-link Repair Double-strand Break Repair Via Synthesis-dependent Strand Annealing Resolution Of Mitotic Recombination Intermediates Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint T-circle Formation Telomeric Loop Disassembly Telomere Maintenance Via Telomere Trimming
Pathways		Fanconi Anemia Pathway	HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 26426971 29273807) Schizophrenia ( 25056061 29483656)
Interacting Genes		44 interacting genes: BRCA2 BRCC3 CAPN1 CBY2 CDK1 COG6 CTBP1 CYP19A1 CYP2E1 DOK5 ERCC4 FANCA FANCC FANCE FANCF FTSJ3 GABPB1 GATA1 GOLGA2 HES1 HGS IHO1 IKZF3 KRT13 KRT19 LNX2 MEOX2 NECAB2 NLGN3 PSMB1 RINT1 RTN2 SAMD3 SSX2IP TADA2A TCEANC TFIP11 TLE5 TPRX1 UIMC1 USHBP1 XRCC3 ZBED1 ZBTB1	22 interacting genes: BAP1 BCAS3 CXCL1 FANCG GREB1 ITIH5 LRATD2 MRC2 OSGIN1 PALB2 PSMC3IP RAD51 RAD51C RAD51D RNF20 SCGB3A1 SERPINB5 SNAI1 SWSAP1 TFF1 ZNHIT3 ZSWIM7
Entrez ID		2189	7517
HPRD ID		04262	07201
Ensembl ID		ENSG00000221829	ENSG00000126215
Uniprot IDs		O15287 Q53XM5	O43542 Q53XC8
PDB IDs
Enriched GO Terms of Interacting Partners?
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