ASXL1 and FOXK2

Number of citations of the paper that reports this interaction (PubMedID 32683582)
3

Data Source:
BioGRID (two hybrid)

		ASXL1	FOXK2
Description		ASXL transcriptional regulator 1	forkhead box K2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm PR-DUB Complex	Chromatin Nucleus Nucleoplasm Mitochondrion Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Protein Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Metal Ion Binding	Magnesium Ion Binding Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Cell Morphogenesis Heart Morphogenesis Animal Organ Morphogenesis Negative Regulation Of Lipid Storage Hemopoiesis Response To Retinoic Acid Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Monoubiquitinated Histone H2A Deubiquitination Regulation Of Kidney Size Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Thymus Development Bone Marrow Development Homeostasis Of Number Of Cells Lung Saccule Development Glomerular Visceral Epithelial Cell Development	Negative Regulation Of Transcription By RNA Polymerase II Cellular Glucose Homeostasis Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Autophagy Regulation Of Glucose Metabolic Process Response To Starvation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Canonical Glycolysis
Pathways		UCH proteinases	UCH proteinases
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908) Red cell distribution width ( 32888494)	Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Lean body mass ( 28552196) Letter-number span reordering ( 31596458) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		17 interacting genes: APP DEFB115 DEFB116 FASN FOXK1 FOXK2 GOLGA6L9 H1-2 ID1 IRAG1 MRPS7 NCOA6 POLD1 SRM SRPK1 STAT3 UBC	11 interacting genes: ASXL1 ESR1 HCFC1 IL2 MTA3 RBBP4 RBBP7 RCOR1 SIN3A TBL1X TBL1XR1
Entrez ID		171023	3607
HPRD ID		16516	00982
Ensembl ID		ENSG00000171456	ENSG00000141568
Uniprot IDs		Q498B9 Q8IXJ9	Q01167
PDB IDs			1JXS 2C6Y
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?