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DDX3X and PIN1
Number of citations of the paper that reports this interaction (PubMedID
16055720
)
92
Data Source:
BioGRID
(pull down)
DDX3X
PIN1
Description
DEAD-box helicase 3 X-linked
peptidylprolyl cis/trans isomerase, NIMA-interacting 1
Image
GO Annotations
Cellular Component
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Plasma Membrane
Cytoplasmic Stress Granule
Lamellipodium
Cell Leading Edge
Secretory Granule Lumen
P Granule
Extracellular Exosome
NLRP3 Inflammasome Complex
Ficolin-1-rich Granule Lumen
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Nuclear Speck
Midbody
Ciliary Basal Body
Neuron Projection
Glutamatergic Synapse
Postsynaptic Cytosol
Molecular Function
DNA Binding
DNA Helicase Activity
RNA Binding
RNA Helicase Activity
MRNA Binding
GTPase Activity
Protein Binding
ATP Binding
Transcription Factor Binding
Poly(A) Binding
Eukaryotic Initiation Factor 4E Binding
ATP Hydrolysis Activity
Nucleoside-triphosphatase Activity
Translation Initiation Factor Binding
RNA Strand Annealing Activity
RNA Stem-loop Binding
Gamma-tubulin Binding
Ribosomal Small Subunit Binding
CTPase Activity
Protein Serine/threonine Kinase Activator Activity
Cadherin Binding
MRNA 5'-UTR Binding
Peptidyl-prolyl Cis-trans Isomerase Activity
Cytoskeletal Motor Activity
Protein Binding
Beta-catenin Binding
Cis-trans Isomerase Activity
Mitogen-activated Protein Kinase Kinase Binding
GTPase Activating Protein Binding
Tau Protein Binding
Phosphoserine Residue Binding
Phosphothreonine Residue Binding
Phosphoprotein Binding
Biological Process
Translational Initiation
Chromosome Segregation
Gamete Generation
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Response To Virus
RNA Secondary Structure Unwinding
Positive Regulation Of Gene Expression
Wnt Signaling Pathway
Negative Regulation Of Translation
Cell Differentiation
Positive Regulation Of Cell Growth
Negative Regulation Of Cell Growth
Primary MiRNA Processing
Negative Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Protein Autophosphorylation
DNA Duplex Unwinding
Positive Regulation Of Interferon-alpha Production
Positive Regulation Of Interferon-beta Production
Stress Granule Assembly
Positive Regulation Of Toll-like Receptor 7 Signaling Pathway
Positive Regulation Of Toll-like Receptor 8 Signaling Pathway
Intracellular Signal Transduction
Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress
Mature Ribosome Assembly
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Viral Genome Replication
Innate Immune Response
Positive Regulation Of Translation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Translational Initiation
Lipid Homeostasis
Cellular Response To Arsenic-containing Substance
Cellular Response To Osmotic Stress
Positive Regulation Of Chemokine (C-C Motif) Ligand 5 Production
Positive Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Canonical Wnt Signaling Pathway
Intrinsic Apoptotic Signaling Pathway
Cellular Response To Virus
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of NLRP3 Inflammasome Complex Assembly
Negative Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Protein Acetylation
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Protein K63-linked Ubiquitination
Protein Localization To Cytoplasmic Stress Granule
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Protein Peptidyl-prolyl Isomerization
Response To Hypoxia
Regulation Of Protein Phosphorylation
Positive Regulation Of Protein Phosphorylation
Cell Cycle
Regulation Of Mitotic Nuclear Division
Regulation Of Gene Expression
Neuron Differentiation
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Protein Stability
Negative Regulation Of Protein Binding
Positive Regulation Of Protein Binding
Regulation Of Cytokinesis
Positive Regulation Of Protein Dephosphorylation
Negative Regulation Of Protein Catabolic Process
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of Neuron Apoptotic Process
Positive Regulation Of GTPase Activity
Positive Regulation Of Transcription By RNA Polymerase II
Microtubule Polymerization
Synapse Organization
Protein Stabilization
Positive Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Negative Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Protein Localization To Nucleus
Negative Regulation Of Amyloid-beta Formation
Negative Regulation Of Cell Motility
Pathways
Neutrophil degranulation
ISG15 antiviral mechanism
RHO GTPases Activate NADPH Oxidases
Regulation of TP53 Activity through Phosphorylation
PI5P Regulates TP53 Acetylation
Negative regulators of DDX58/IFIH1 signaling
Drugs
Beta-(2-Naphthyl)-Alanine
3,6,9,12,15,18-HEXAOXAICOSANE
Diseases
GWAS
Refractive error (
32231278
)
Sleep duration (
25469926
)
Interacting Genes
98 interacting genes:
APBB1
CETN2
CSNK2A1
DUX4
ESR1
GABRE
HNF4A
IKBKE
IL7R
LINC01232
LINC01554
MAVS
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NEDD4
NFKB2
NUP62
OGT
PIN1
RABEP1
SREK1
SRPK2
SUMO2
TBC1D25
WBP4
XPO1
YWHAQ
ZNF512B
263 interacting genes:
ABI2
ADAMTSL4
ADARB1
AJUBA
AMOT
ANKRD40
AP2A1
APLP1
APP
ARHGEF15
ARID5A
ATCAY
ATN1
ATP5F1B
BAG6
BARD1
BCL11A
BCL2
BCL6
BCLAF1
BRCA1
BRD8
C3orf36
CAPRIN1
CARHSP1
CASP6
CBFA2T3
CBS
CBY2
CCDC153
CCDC184
CCDC33
CCDC6
CCDC88B
CCDC90B
CCNB1
CCNE1
CCNK
CDC25C
CDC27
CDK1
CDK11A
CDK11B
CDK12
CDK2
CDK9
CDKN1B
CENPB
CEP55
CEP76
CHAMP1
CHPF
CNKSR1
COL11A2
CPEB1
CPNE6
CSAD
CSNK2A1
CSNK2A2
CSNK2B
CTNNB1
DAB1
DAB2
DDAH2
DDB1
DDX17
DDX24
DDX3X
DDX5
DEAF1
DHX15
DMPK
DYNC1I1
E2F4
EFS
EFTUD2
EIF3G
EP300
ETV6
EYA2
FAAP20
FADD
FASLG
FHL5
FOS
FOSL1
FOXI1
FOXN1
FOXO4
FOXP2
FRS2
FUCA2
G3BP1
G3BP2
GGA2
GMEB2
GOLGA2
GOLGA6L9
GPAA1
GPHN
GPR152
HADHA
HEXIM2
HNRNPC
HNRNPH1
HNRNPK
HNRNPU
HOMEZ
HOXA1
IKZF1
IKZF3
INO80E
JAKMIP2
JUN
KCTD7
KIF20B
KIF5A
KIFC3
KLHL20
KMT2B
KRT31
KRT34
KRT37
KRT38
KRT40
KRTAP10-1
KRTAP10-3
KRTAP10-6
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP4-2
KRTAP5-9
LCN2
LEPR
LRIF1
MAP1S
MAP3K11
MAPT
MCL1
MDFI
MED1
MEOX1
MEOX2
MLLT6
MOCS1
MTFR1
MTUS2
MYF5
MYT1
NAB2
NCKIPSD
NCOA3
NCOR2
NEK6
NELFA
NEUROD4
NFATC2
NONO
NR4A3
NUP35
NUP62
PABPC1
PAX6
PBX1
PDLIM7
PKIB
PKM
PKMYT1
PLAGL2
PLEKHG2
PLK1
PML
PNMA1
POLR2A
PRPF8
PRRC1
PTOV1
PTPN1
QARS1
RAB4A
RAF1
RAI1
RARA
RBBP8
RBBP8NL
RBPMS
RELA
REPS1
RNF208
RNPS1
RPL4
RPS6KB1
RUNX2
SCAI
SCYL1
SELENOV
SFPQ
SGK1
SHKBP1
SMAD3
SNCAIP
SNRNP200
SOCS3
SREK1
SRRM1
SRRM2
SRSF11
SSBP2
SSBP3
SSBP4
SSC5D
STIL
SUPT5H
TAB3
TBC1D4
TCF12
TCF4
TFG
TFPT
THAP7
THRAP3
TLE3
TNIP1
TNS2
TOP2A
TOX3
TP53
TP63
TP73
TRAF1
TRAF2
TRIM27
TRIM59
TRIP6
TRMT2A
TSC2
TSC22D4
TUT1
U2AF2
UBB
UBQLN2
UBQLN4
UBXN2B
UNC119
VIRMA
WEE1
WIZ
WRNIP1
XRCC6
ZBTB14
ZBTB2
ZBTB22
ZBTB42
ZBTB7B
ZBTB9
ZCCHC10
ZMIZ2
ZNF446
ZNF449
ZNF526
ZNF768
ZNF783
Entrez ID
1654
5300
HPRD ID
02154
03031
Ensembl ID
ENSG00000215301
ENSG00000127445
Uniprot IDs
A0A2R8Y7T2
A0A2R8YFS5
O00571
Q13526
PDB IDs
2I4I
2JGN
3JRV
4O2C
4O2E
4O2F
4PX9
4PXA
5E7I
5E7J
5E7M
6CZ5
6O5F
1F8A
1I6C
1I8G
1I8H
1NMV
1NMW
1PIN
1ZCN
2F21
2ITK
2KBU
2KCF
2LB3
2M8I
2M8J
2M9E
2M9F
2M9I
2M9J
2N1O
2Q5A
2RUC
2RUD
2RUQ
2RUR
2XP3
2XP4
2XP5
2XP6
2XP7
2XP8
2XP9
2XPA
2XPB
2ZQS
2ZQT
2ZQU
2ZQV
2ZR4
2ZR5
2ZR6
3I6C
3IK8
3IKD
3IKG
3JYJ
3KAB
3KAC
3KAD
3KAF
3KAG
3KAH
3KAI
3KCE
3NTP
3ODK
3OOB
3TC5
3TCZ
3TDB
3WH0
4GWT
4GWV
4QIB
4TNS
4TYO
4U84
4U85
4U86
5B3W
5B3X
5B3Y
5B3Z
5BMY
5GPH
5UY9
5VTI
5VTJ
5VTK
6DUN
6O33
6O34
6SVC
6SVE
6SVH
6VAJ
Enriched GO Terms of Interacting Partners
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