CYBA and CPT1A

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		CYBA	CPT1A
Description		cytochrome b-245 alpha chain	carnitine palmitoyltransferase 1A
Image
GO Annotations	Cellular Component	Stress Fiber Nucleus Endosome Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Focal Adhesion Membrane Apical Plasma Membrane Secretory Granule Dendrite Phagocytic Vesicle Membrane Specific Granule Membrane NADPH Oxidase Complex Neuronal Cell Body Tertiary Granule Membrane Perinuclear Endoplasmic Reticulum	Mitochondrion Mitochondrial Outer Membrane Membrane Integral Component Of Mitochondrial Outer Membrane
	Molecular Function	Protein Binding Electron Transfer Activity Superoxide-generating NAD(P)H Oxidase Activity SH3 Domain Binding Heme Binding Metal Ion Binding Protein Heterodimerization Activity	Carnitine O-palmitoyltransferase Activity Identical Protein Binding Palmitoleoyltransferase Activity
	Biological Process	Response To Hypoxia Positive Regulation Of Endothelial Cell Proliferation Negative Regulation Of Glomerular Filtration By Angiotensin Superoxide Metabolic Process Inflammatory Response Response To Xenobiotic Stimulus Response To Activity Smooth Muscle Hypertrophy Cytochrome Complex Assembly Electron Transport Chain Positive Regulation Of Cell Growth Response To Nutrient Levels Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Superoxide Anion Generation Positive Regulation Of NAD(P)H Oxidase Activity Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Superoxide Anion Generation Innate Immune Response Respiratory Burst Positive Regulation Of Smooth Muscle Cell Proliferation Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Phagocytosis Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Mucus Secretion Response To Interleukin-1 Cellular Response To Mechanical Stimulus Cellular Response To Glucose Stimulus Cellular Response To Tumor Necrosis Factor Cellular Response To Organic Cyclic Compound Cellular Response To Gamma Radiation Positive Regulation Of Defense Response To Bacterium Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Response To Aldosterone Cellular Response To Angiotensin Cellular Response To L-glutamine	Long-chain Fatty Acid Metabolic Process Glucose Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Triglyceride Metabolic Process Carnitine Shuttle Response To Xenobiotic Stimulus Carnitine Metabolic Process Regulation Of Lipid Storage Response To Organic Cyclic Compound Epithelial Cell Differentiation Response To Nutrient Levels Positive Regulation Of Fatty Acid Beta-oxidation Eating Behavior Response To Alkaloid Response To Ethanol Response To Antibiotic Regulation Of Insulin Secretion Cellular Response To Fatty Acid Liver Regeneration Response To Tetrachloromethane
Pathways		ROS and RNS production in phagocytes Cross-presentation of particulate exogenous antigens (phagosomes) Detoxification of Reactive Oxygen Species VEGFA-VEGFR2 Pathway RHO GTPases Activate NADPH Oxidases Neutrophil degranulation CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RAC3 GTPase cycle WNT5:FZD7-mediated leishmania damping	RORA activates gene expression PPARA activates gene expression Carnitine metabolism Signaling by Retinoic Acid
Drugs		Dextromethorphan	Levocarnitine Glyburide Perhexiline
Diseases
GWAS		Glycated hemoglobin levels ( 24647736) Hair color ( 26926045)	Apolipoprotein A1 levels ( 32203549) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) HDL cholesterol levels ( 32203549) Lipid metabolism phenotypes ( 22286219) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Obesity-related traits ( 23251661) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Triglyceride levels ( 32203549 32154731) Urate levels ( 31578528)
Interacting Genes		13 interacting genes: APPBP2 CPT1A CYBB MDFI NCF1 NCF2 NCF4 NOX1 PSMA3 RAC1 RBPMS RCHY1 UPF2	8 interacting genes: BCL2 CLIC1 CYBA HSPA5 KBTBD7 NPDC1 NR4A1 UBC
Entrez ID		1535	1374
HPRD ID		01989	02755
Ensembl ID		ENSG00000051523	ENSG00000110090
Uniprot IDs		B4DT46 H3BNP7 P13498	A0A024R5F4 B2RAQ8 P50416 Q8WZ48
PDB IDs		1WLP	2LE3
Enriched GO Terms of Interacting Partners?
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