CPT1A

Description		carnitine palmitoyltransferase 1A
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Membrane Integral Component Of Mitochondrial Outer Membrane
	Molecular Function	Carnitine O-palmitoyltransferase Activity Identical Protein Binding Palmitoleoyltransferase Activity
	Biological Process	Long-chain Fatty Acid Metabolic Process Glucose Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Triglyceride Metabolic Process Carnitine Shuttle Response To Xenobiotic Stimulus Carnitine Metabolic Process Regulation Of Lipid Storage Response To Organic Cyclic Compound Epithelial Cell Differentiation Response To Nutrient Levels Positive Regulation Of Fatty Acid Beta-oxidation Eating Behavior Response To Alkaloid Response To Ethanol Response To Antibiotic Regulation Of Insulin Secretion Cellular Response To Fatty Acid Liver Regeneration Response To Tetrachloromethane
Pathways		RORA activates gene expression PPARA activates gene expression Carnitine metabolism Signaling by Retinoic Acid
Drugs		Levocarnitine Glyburide Perhexiline
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) HDL cholesterol levels ( 32203549) Lipid metabolism phenotypes ( 22286219) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Obesity-related traits ( 23251661) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Triglyceride levels ( 32203549 32154731) Urate levels ( 31578528)
Interacting Genes		8 interacting genes: BCL2 CLIC1 CYBA HSPA5 KBTBD7 NPDC1 NR4A1 UBC
Entrez ID		1374
HPRD ID		02755
Ensembl ID		ENSG00000110090
Uniprot IDs		A0A024R5F4 B2RAQ8 P50416 Q8WZ48
PDB IDs		2LE3
Enriched GO Terms of Interacting Partners?
Tagcloud ?