HAUS1 and BLOC1S6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		HAUS1	BLOC1S6
Description		HAUS augmin like complex subunit 1	biogenesis of lysosomal organelles complex 1 subunit 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Centrosome Cytosol HAUS Complex Mitotic Spindle Microtubule	Cytoplasm Endosome Cytosol Extrinsic Component Of Membrane Transport Vesicle BLOC-1 Complex Presynapse Axon Cytoplasm
	Molecular Function	Molecular_function Protein Binding	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding
	Biological Process	Centrosome Cycle Spindle Assembly Cell Division	Blood Coagulation Anterograde Axonal Transport Synaptic Vesicle Docking Melanocyte Differentiation Neuron Projection Development Melanosome Transport Melanosome Organization Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Endosome To Melanosome Transport Intracellular Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation Membrane Fusion
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS
Interacting Genes		82 interacting genes: AK8 ARFIP2 ATP6V1D BFSP2 BLOC1S6 BORCS6 C3orf62 CAGE1 CBY2 CCDC136 CCDC57 CCHCR1 CDR2 CENPP CEP170P1 CEP44 CEP55 CEP57L1 CEP63 CEP70 DCTN2 DMD DTNBP1 FAM161B FGFR1OP2 GOLGA2 HGS HOOK2 IFIT3 IFT20 INCA1 KDM1A KIFC3 KRT1 KRT15 KRT18 KRT19 KRT3 KRT31 KRT38 KRT40 KXD1 LDOC1 LURAP1 MAD1L1 MAGEA6 MCM10 MCM3 MED4 MED7 MIPOL1 MTUS2 NDC80 NECAB2 NINL NUP54 NUP62 ODAD1 PDE4DIP PIBF1 PKN1 POLR3C SPAG5 SSC5D STX11 SYCE1 SYCE3 TEAD4 TFIP11 TFPT TRAF1 TRIM23 TRIM27 TRIM54 TRIM69 TSG101 TXN2 USHBP1 VPS37C VPS52 WASHC3 ZNF471	50 interacting genes: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 C4orf46 CCDC136 CCDC22 CCHCR1 CCR2 CDK5R1 CEP44 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 INSYN1 KRT13 KRT72 LURAP1 MED21 MLPH NDC80 NDN NTAQ1 NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 RINT1 SEMA6D SKA1 SLC4A1 SMN1 SMN2 SNAPIN STX11 STX12 STX1A SYCE3 TPM1 TPM3 TRAK1 WASHC3
Entrez ID		115106	26258
HPRD ID		16385	16055
Ensembl ID		ENSG00000152240	ENSG00000104164
Uniprot IDs		Q96CS2	B3KY40 H3BST1 Q9UL45
PDB IDs
Enriched GO Terms of Interacting Partners?
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