HAUS1 and TRIM69

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		HAUS1	TRIM69
Description		HAUS augmin like complex subunit 1	tripartite motif containing 69
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Centrosome Cytosol HAUS Complex Mitotic Spindle Microtubule	Nucleus Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Molecular_function Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Centrosome Cycle Spindle Assembly Cell Division	Apoptotic Process Protein Ubiquitination
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Estimated glomerular filtration rate in non-diabetics ( 31451708)
Interacting Genes		82 interacting genes: AK8 ARFIP2 ATP6V1D BFSP2 BLOC1S6 BORCS6 C3orf62 CAGE1 CBY2 CCDC136 CCDC57 CCHCR1 CDR2 CENPP CEP170P1 CEP44 CEP55 CEP57L1 CEP63 CEP70 DCTN2 DMD DTNBP1 FAM161B FGFR1OP2 GOLGA2 HGS HOOK2 IFIT3 IFT20 INCA1 KDM1A KIFC3 KRT1 KRT15 KRT18 KRT19 KRT3 KRT31 KRT38 KRT40 KXD1 LDOC1 LURAP1 MAD1L1 MAGEA6 MCM10 MCM3 MED4 MED7 MIPOL1 MTUS2 NDC80 NECAB2 NINL NUP54 NUP62 ODAD1 PDE4DIP PIBF1 PKN1 POLR3C SPAG5 SSC5D STX11 SYCE1 SYCE3 TEAD4 TFIP11 TFPT TRAF1 TRIM23 TRIM27 TRIM54 TRIM69 TSG101 TXN2 USHBP1 VPS37C VPS52 WASHC3 ZNF471	53 interacting genes: AIFM2 APP ASNS ATP5MC1 BEX2 BIN3 C4orf45 CDSN DVL1 ETFDH FAM110A FAM161A FAM90A1 FKBP1B GEM HAUS1 HGS IYD KLHL38 KRT17 LARP1B LYSMD1 MAGEA4 MAJIN MED20 MID2 NEK8 NTAQ1 PML POLR3K PPP1R18 RECK RINT1 RSPH14 SF1 SF3A3 SKIL STMN3 SYCE2 SYNE4 TNNT2 TRIM44 TRIM54 TRIM55 TRIM63 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N WASHC1 WWOX ZNF483
Entrez ID		115106	140691
HPRD ID		16385	11518
Ensembl ID		ENSG00000152240	ENSG00000185880
Uniprot IDs		Q96CS2	H0YL66 Q86WT6
PDB IDs			4NQJ 6YXE
Enriched GO Terms of Interacting Partners?
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