BLOC1S6 and MLPH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BLOC1S6	MLPH
Description		biogenesis of lysosomal organelles complex 1 subunit 6	melanophilin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Cytosol Extrinsic Component Of Membrane Transport Vesicle BLOC-1 Complex Presynapse Axon Cytoplasm	Dendrite Cortical Actin Cytoskeleton Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding	Actin Binding Protein Binding Myosin Binding Protein-macromolecule Adaptor Activity Small GTPase Binding Metal Ion Binding
	Biological Process	Blood Coagulation Anterograde Axonal Transport Synaptic Vesicle Docking Melanocyte Differentiation Neuron Projection Development Melanosome Transport Melanosome Organization Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Endosome To Melanosome Transport Intracellular Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation Membrane Fusion	Intracellular Protein Transport Melanosome Transport
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS			Central corneal thickness ( 32528159) Heel bone mineral density ( 30598549 28869591) Height ( 33713608) Intraocular pressure ( 29617998) Prostate cancer ( 21743057)
Interacting Genes		50 interacting genes: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 C4orf46 CCDC136 CCDC22 CCHCR1 CCR2 CDK5R1 CEP44 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 INSYN1 KRT13 KRT72 LURAP1 MED21 MLPH NDC80 NDN NTAQ1 NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 RINT1 SEMA6D SKA1 SLC4A1 SMN1 SMN2 SNAPIN STX11 STX12 STX1A SYCE3 TPM1 TPM3 TRAK1 WASHC3	7 interacting genes: BLOC1S6 C1orf216 MTDH MYO5A RAB27A RAB27B RECK
Entrez ID		26258	79083
HPRD ID		16055	09409
Ensembl ID		ENSG00000104164	ENSG00000115648
Uniprot IDs		B3KY40 H3BST1 Q9UL45	A0A024R4D3 Q9BV36
PDB IDs
Enriched GO Terms of Interacting Partners?
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