RPP14 and NOVA1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		RPP14	NOVA1
Description		ribonuclease P/MRP subunit p14	NOVA alternative splicing regulator 1
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Multimeric Ribonuclease P Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	RNA Binding MRNA Binding Protein Binding Sequence-specific MRNA Binding
	Biological Process	TRNA 5'-leader Removal RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing Regulation Of Gene Expression Regulation Of RNA Metabolic Process Negative Regulation Of Cold-induced Thermogenesis
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Height ( 28552196) Hemoglobin levels ( 32327693) Mitochondrial heteroplasmy measurement ( 33731350) Platelet distribution width ( 32888494) Refractive error ( 32231278) Rheumatoid arthritis (ACPA-positive) ( 24532676) Total cholesterol levels ( 30275531)	BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 28892062) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Cognitive decline rate in late mild cognitive impairment ( 26252872) Eosinophilic esophagitis ( 25407941) Finger osteoarthritis severity (hand Klsum) ( 33055079) Hand grip strength ( 29691431) Metabolite levels ( 23823483) Migraine ( 27182965) Neuritic plaque ( 31497858) Overweight status ( 25133637) Peanut allergy ( 29030101) Plasma anti-thyroid peroxidase levels ( 29678681) Zinc levels ( 26025379)
Interacting Genes		22 interacting genes: A2M ACTN2 ATP5F1B CAPZB DOCK7 EXOSC8 GEMIN2 IGSF21 KMT2B LIMD1 MSH2 NOVA1 PKM POP4 POP5 PSME1 RPP25 RPP30 RPP38 RPP40 WIZ ZNF277	5 interacting genes: APP PCBP1 RPP14 SMARCC2 SRPK1
Entrez ID		11102	4857
HPRD ID		18001	03693
Ensembl ID		ENSG00000163684	ENSG00000139910
Uniprot IDs		O95059	B7Z770 P51513
PDB IDs		6AHR 6AHU	1DT4 2ANN 2ANR
Enriched GO Terms of Interacting Partners?
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