SEC23B and FBXW5

Number of citations of the paper that reports this interaction (PubMedID 30596474)
19

Data Source:
BioGRID (affinity chromatography technology, unspecified method, affinity chromatography technology)

		SEC23B	FBXW5
Description		SEC23 homolog B, COPII coat complex component	F-box and WD repeat domain containing 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding	Protein Binding Protein Kinase Binding
	Biological Process	Intracellular Protein Transport Regulation Of Catalytic Activity COPII-coated Vesicle Cargo Loading	Regulation Of Mitotic Nuclear Division Regulation Of Centrosome Duplication Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways			Association of TriC/CCT with target proteins during biosynthesis Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Blood protein levels ( 29875488) Heel bone mineral density ( 30598549) Keratoconus ( 33649486) Plateletcrit ( 32888494)
Interacting Genes		26 interacting genes: CPSF7 DTX2 FATE1 FBXW5 GALNT1 HOXA3 KDELR1 MAN2A1 NINL PRRC1 RIN1 SEC23A SEC24C SEC24D SKP1 SNRPC SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 TRIM55 TRIM63 UGT1A1	36 interacting genes: ADAMTSL4 CYP1A1 CYSRT1 EFEMP2 FAM168A FBLN2 KRT31 KRT34 KRT37 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-1 KRTAP4-12 KRTAP6-3 KRTAP9-3 KRTAP9-4 MDFI MID2 MTUS2 MYB NBPF19 NLK NOTCH2NLA PLEKHF2 S100B SASS6 SEC23B SKP1 TRIM27 TSC2 UBE2R2 VWC2
Entrez ID		10483	54461
HPRD ID		11543	10955
Ensembl ID		ENSG00000101310	ENSG00000159069
Uniprot IDs		A0A2R8YFH5 Q15437	A0A024R8H7 Q969U6
PDB IDs
Enriched GO Terms of Interacting Partners?
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