SEC23B and CPSF7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		SEC23B	CPSF7
Description		SEC23 homolog B, COPII coat complex component	cleavage and polyadenylation specific factor 7
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Nucleus Nucleoplasm Cytoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding	RNA Binding Protein Binding
	Biological Process	Intracellular Protein Transport Regulation Of Catalytic Activity COPII-coated Vesicle Cargo Loading	Protein Tetramerization Protein Heterotetramerization Pre-mRNA Cleavage Required For Polyadenylation MRNA Alternative Polyadenylation Messenger Ribonucleoprotein Complex Assembly
Pathways			mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs RHOBTB1 GTPase cycle
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Interacting Genes		26 interacting genes: CPSF7 DTX2 FATE1 FBXW5 GALNT1 HOXA3 KDELR1 MAN2A1 NINL PRRC1 RIN1 SEC23A SEC24C SEC24D SKP1 SNRPC SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 TRIM55 TRIM63 UGT1A1	62 interacting genes: APBB1 ARMC7 ATXN1 CATSPER1 CCDC86 CFAP206 CLK2 CSNK2A1 DVL2 EPM2AIP1 EWSR1 GAS8 GCC1 GRB2 GUCD1 HINT1 HNRNPF ITCH LENG8 LNX1 MAILR MIR1-1 MIR1-2 MIR10B MIR128-2 MIR141 MIR155 MIR16-1 MIR17 MIR18B MIR199A1 MIR19A MIR19B1 MIR25 MIR29C MIR34B MIR7-1 MIR9-2 MIR93 MIRLET7B NCK2 NUDT21 OGT PATZ1 PID1 PRKAA2 PRMT2 RBM10 RUNX1T1 SEC23B SMAD3 SNRNP25 SNX18 SORBS3 SPG21 SRPK2 SUMO2 TLE5 TNS2 U2AF2 WBP4 WWOX
Entrez ID		10483	79869
HPRD ID		11543	16906
Ensembl ID		ENSG00000101310	ENSG00000149532
Uniprot IDs		A0A2R8YFH5 Q15437	B4DGF8 Q8N684
PDB IDs			3N9U
Enriched GO Terms of Interacting Partners?
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