PATJ and TJP3

Number of citations of the paper that reports this interaction (PubMedID 12021270)
53

Data Source:
HPRD (in vitro, in vivo)

		PATJ	TJP3
Description		PATJ crumbs cell polarity complex component	tight junction protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cell Junction Centriolar Satellite Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Nucleoplasm Plasma Membrane Bicellular Tight Junction Cell Junction
	Molecular Function	Protein Binding	Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Microtubule Organizing Center Organization Establishment Of Apical/basal Cell Polarity Intracellular Signal Transduction Regulation Of Microtubule Cytoskeleton Organization Tight Junction Assembly	Maintenance Of Blood-brain Barrier Cell-cell Junction Organization Establishment Of Endothelial Intestinal Barrier Cell-cell Adhesion Protein Localization To Cell-cell Junction Positive Regulation Of Blood-brain Barrier Permeability
Pathways
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30582445) Autism spectrum disorders (social interaction) ( 32624584) Daytime nap ( 33568662) Excessive daytime sleepiness ( 27992416) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes ( 30297969)	Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect) ( 31372216)
Interacting Genes		35 interacting genes: ADGRB1 ASIC3 CACNG2 CEP57L1 CINP CLDN1 CNKSR2 CRB3 CRIPT DDX18 GIPC2 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D HDAC7 HOMER1 KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 NECAB2 NLGN2 NRXN2 PALS1 PARD3 PAX6 PHYH PRDM16 SCN4A SCN5A TJP3	5 interacting genes: CLDN1 FASLG GJC1 PATJ TJP1
Entrez ID		10207	27134
HPRD ID		04434	18194
Ensembl ID		ENSG00000132849	ENSG00000105289
Uniprot IDs			O95049
PDB IDs			3KFV
Enriched GO Terms of Interacting Partners?
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