PATJ and KCNJ15

Number of citations of the paper that reports this interaction (PubMedID 9647694)
29

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		PATJ	KCNJ15
Description		PATJ crumbs cell polarity complex component	potassium inwardly rectifying channel subfamily J member 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cell Junction Centriolar Satellite Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding	Inward Rectifier Potassium Channel Activity Protein Binding
	Biological Process	Microtubule Organizing Center Organization Establishment Of Apical/basal Cell Polarity Intracellular Signal Transduction Regulation Of Microtubule Cytoskeleton Organization Tight Junction Assembly	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways			Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Yohimbine Butamben
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30582445) Autism spectrum disorders (social interaction) ( 32624584) Daytime nap ( 33568662) Excessive daytime sleepiness ( 27992416) Sleep traits (multi-trait analysis) ( 27992416) Type 2 diabetes ( 30297969)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Body shape index ( 34021172) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Metabolite levels ( 23823483) Monocyte count ( 32888494) Non-response to antidepressants and depression ( 27622933) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		35 interacting genes: ADGRB1 ASIC3 CACNG2 CEP57L1 CINP CLDN1 CNKSR2 CRB3 CRIPT DDX18 GIPC2 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D HDAC7 HOMER1 KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 NECAB2 NLGN2 NRXN2 PALS1 PARD3 PAX6 PHYH PRDM16 SCN4A SCN5A TJP3	16 interacting genes: CBR3 CTSE DSCAM IL16 KCNE1 KCNJ16 KCNJ2 KCNJ5 LRP8 MTCH1 PATJ SLC39A2 SNTA1 SON TOR1B TTC3
Entrez ID		10207	3772
HPRD ID		04434	03659
Ensembl ID		ENSG00000132849	ENSG00000157551
Uniprot IDs			Q99712
PDB IDs
Enriched GO Terms of Interacting Partners?
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