RNF41 and N4BP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RNF41	N4BP3
Description		ring finger protein 41	NEDD4 binding protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Tubular Network	Axon Dendrite Cytoplasmic Vesicle
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding Receptor Tyrosine Kinase Binding Small GTPase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Protein Polyubiquitination Autophagy Negative Regulation Of Cell Population Proliferation Proteasomal Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Cell Migration Regulation Of MAPK Cascade Positive Regulation Of Protein Catabolic Process Protein Autoubiquitination Regulation Of Protein Kinase B Signaling Extrinsic Apoptotic Signaling Pathway Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process	Nervous System Development
Pathways		Downregulation of ERBB2:ERBB3 signaling Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Asthma ( 31619474) Height ( 34054925)	SAPHO syndrome ( 33816493)
Interacting Genes		49 interacting genes: ADRB2 AP2S1 APP ARL6IP4 ASB6 BIRC6 C1orf109 CLEC9A ENOPH1 ERBB3 ERBB4 GDF11 IRS4 ISCA2 KDM3B LEPR LZTS2 MAGEL2 MARK2 MEOX2 MNAT1 MTNR1A MTNR1B MTURN N4BP3 NEUROD4 ORMDL2 PPP1R1A RAD23A RFC4 RNF166 RRM2B SRR SUOX TBATA TCEANC TRIM32 TRIM8 TSG101 TTC1 UBASH3A UBASH3B UBE2D3 UBE2K UBE2U UBE2Z USP8 VPS52 ZAP70	18 interacting genes: CCDC146 CCDC17 CNKSR3 CTDSP2 ENKD1 FXR1 LMO4 NEDD4 NTAQ1 PRR35 RFC5 RNF41 RUSC1 SDCBP SHANK3 SPG21 UBASH3A YWHAG
Entrez ID		10193	23138
HPRD ID		11520	10108
Ensembl ID		ENSG00000181852	ENSG00000145911
Uniprot IDs		A0A024RB33 Q9H4P4	O15049
PDB IDs		2FZP 2GWF
Enriched GO Terms of Interacting Partners?
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