CDK3 and CKS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CDK3	CKS2
Description		cyclin dependent kinase 3	CDC28 protein kinase regulatory subunit 2
Image
GO Annotations	Cellular Component	Nucleus	Cyclin-dependent Protein Kinase Holoenzyme Complex SCF Ubiquitin Ligase Complex
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Chromatin Binding Protein Binding Protein Kinase Binding Histone Binding Ubiquitin Binding Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Population Proliferation G0 To G1 Transition Cell Division Regulation Of Cell Cycle	Regulation Of Transcription By RNA Polymerase II Meiosis I Regulation Of Mitotic Cell Cycle Cell Population Proliferation Mitotic Cell Cycle Phase Transition Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Division
Pathways
Drugs
Diseases
GWAS			Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		41 interacting genes: APP CABLES1 CABLES2 CCNA2 CCNC CCND3 CCNE1 CCNE2 CCNH CCNI CDC37 CDKN1A CDKN1B CDKN3 CKS1B CKS2 E2F1 E2F2 E2F3 FOXJ1 FOXP2 FRS2 KIR3DL1 LHX3 LHX4 MEOX2 NAP1L1 NEDD4L NELFA OR2G6 OTX2 PAX5 PAX6 PAX8 PPARA RACGAP1 RB1 SPDYE4 STN1 TRIM55 TRIM63	15 interacting genes: BLZF1 CCNA1 CCNB2 CDC37 CDK1 CDK3 CKS1B EEF1A1 GRB2 HSP90AA1 LDHB SSBP1 TSC22D4 UNC119 VTN
Entrez ID		1018	1164
HPRD ID		00446	00300
Ensembl ID		ENSG00000250506	ENSG00000123975
Uniprot IDs		Q00526	P33552
PDB IDs		1LFN	1CKS 4Y72 4YC3 5HQ0 5LQF 6GU2 6GU3 6GU4 6GU6 6GU7
Enriched GO Terms of Interacting Partners?
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