CDK3 and CDKN3

Number of citations of the paper that reports this interaction (PubMedID 8242750)
529

Data Source:
HPRD (two hybrid, in vivo)

		CDK3	CDKN3
Description		cyclin dependent kinase 3	cyclin dependent kinase inhibitor 3
Image
GO Annotations	Cellular Component	Nucleus	Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Population Proliferation G0 To G1 Transition Cell Division Regulation Of Cell Cycle	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Population Proliferation Peptidyl-tyrosine Dephosphorylation Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS			Cortical volume ( 32963231) Dental caries ( 23259602) Endometrial cancer (Non-endometrioid histology) ( 30093612) High myopia ( 31816047) Metabolite levels ( 23823483) Metabolite levels (X-11787) ( 23934736) Monobrow thickness ( 26926045) Myopia ( 27182965) Refractive error ( 32231278) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)
Interacting Genes		41 interacting genes: APP CABLES1 CABLES2 CCNA2 CCNC CCND3 CCNE1 CCNE2 CCNH CCNI CDC37 CDKN1A CDKN1B CDKN3 CKS1B CKS2 E2F1 E2F2 E2F3 FOXJ1 FOXP2 FRS2 KIR3DL1 LHX3 LHX4 MEOX2 NAP1L1 NEDD4L NELFA OR2G6 OTX2 PAX5 PAX6 PAX8 PPARA RACGAP1 RB1 SPDYE4 STN1 TRIM55 TRIM63	9 interacting genes: CDC25A CDK1 CDK2 CDK3 CEBPA MS4A3 NCOA3 PPP1R12A ROCK2
Entrez ID		1018	1033
HPRD ID		00446	00450
Ensembl ID		ENSG00000250506	ENSG00000100526
Uniprot IDs		Q00526	G3V2J7 Q16667
PDB IDs		1LFN	1FPZ 1FQ1
Enriched GO Terms of Interacting Partners?
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