TOM1 and NAA11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TOM1	NAA11
Description		target of myb1 membrane trafficking protein	N-alpha-acetyltransferase 11, NatA catalytic subunit
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Azurophil Granule Membrane Specific Granule Membrane Extracellular Exosome	Nucleoplasm Golgi Apparatus Centrosome Cytosol NatA Complex
	Molecular Function	Protein Binding Clathrin Binding Phosphatidylinositol Binding Ubiquitin Binding	Peptide Alpha-N-acetyltransferase Activity Protein Binding Peptide-serine-N-acetyltransferase Activity Peptide-glutamate-N-acetyltransferase Activity
	Biological Process	Endocytosis Signal Transduction Protein Transport Endosomal Transport	N-terminal Protein Amino Acid Acetylation N-terminal Peptidyl-serine Acetylation N-terminal Peptidyl-glutamic Acid Acetylation
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Cholesterol, total ( 24097068) HDL cholesterol ( 29404214) High density lipoprotein cholesterol levels ( 31217584) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Hippocampal volume in mild cognitive impairment ( 29274321) Inflammatory bowel disease ( 28067908) Low density lipoprotein cholesterol levels ( 32154731) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease ( 29748315) Total cholesterol levels ( 28334899) Triglyceride levels ( 34074324) Ulcerative colitis ( 28067908) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Refractive error ( 32231278) Schizophrenia ( 33169155)
Interacting Genes		24 interacting genes: APP CLTC DAZAP2 DNAL4 EEA1 ILVBL LITAF LRRC20 MAP3K1 MYO6 NAA11 NEDD4 OGT PILRA PTBP2 RPS27 SMURF1 SSBP2 TAB1 TOLLIP UBC UBE2D1 ZFYVE16 ZNF512B	16 interacting genes: ACOT12 AP2M1 BAALC CDC25A CDCA5 CREBRF EHMT2 FRAS1 HIF1A KIFAP3 MTARC1 NAA15 NAA16 TOM1 ZBTB14 ZNF202
Entrez ID		10043	84779
HPRD ID		05265	19248
Ensembl ID		ENSG00000100284	ENSG00000156269
Uniprot IDs		B3KUF5 O60784	Q9BSU3
PDB IDs		1ELK 1WRD 2N2N 2N9D 6J56
Enriched GO Terms of Interacting Partners?
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