TOM1 and ILVBL

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		TOM1	ILVBL
Description		target of myb1 membrane trafficking protein	ilvB acetolactate synthase like
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Azurophil Granule Membrane Specific Granule Membrane Extracellular Exosome	Endoplasmic Reticulum Membrane Acetolactate Synthase Complex Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Clathrin Binding Phosphatidylinositol Binding Ubiquitin Binding	Magnesium Ion Binding Molecular_function Acetolactate Synthase Activity Protein Binding Lyase Activity Thiamine Pyrophosphate Binding Flavin Adenine Dinucleotide Binding
	Biological Process	Endocytosis Signal Transduction Protein Transport Endosomal Transport	Fatty Acid Alpha-oxidation Isoleucine Biosynthetic Process Valine Biosynthetic Process
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Cholesterol, total ( 24097068) HDL cholesterol ( 29404214) High density lipoprotein cholesterol levels ( 31217584) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Hippocampal volume in mild cognitive impairment ( 29274321) Inflammatory bowel disease ( 28067908) Low density lipoprotein cholesterol levels ( 32154731) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease ( 29748315) Total cholesterol levels ( 28334899) Triglyceride levels ( 34074324) Ulcerative colitis ( 28067908) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Loneliness ( 27629369) Metabolite levels ( 23823483)
Interacting Genes		24 interacting genes: APP CLTC DAZAP2 DNAL4 EEA1 ILVBL LITAF LRRC20 MAP3K1 MYO6 NAA11 NEDD4 OGT PILRA PTBP2 RPS27 SMURF1 SSBP2 TAB1 TOLLIP UBC UBE2D1 ZFYVE16 ZNF512B	5 interacting genes: ATXN1 CEP76 ECT2 TOM1 XRCC6
Entrez ID		10043	10994
HPRD ID		05265	16152
Ensembl ID		ENSG00000100284	ENSG00000105135
Uniprot IDs		B3KUF5 O60784	A1L0T0 M0R026
PDB IDs		1ELK 1WRD 2N2N 2N9D 6J56
Enriched GO Terms of Interacting Partners?
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