CDH3 and CDH5

		CDH3	CDH5
Description		cadherin 3	cadherin 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Adherens Junction Integral Component Of Membrane Catenin Complex Cell Junction	Nucleoplasm Plasma Membrane Cell-cell Junction Adherens Junction Bicellular Tight Junction External Side Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Catenin Complex Cell Junction Nuclear Membrane
	Molecular Function	Molecular_function Calcium Ion Binding Cadherin Binding	Signaling Receptor Binding Calcium Ion Binding Protein Binding Beta-catenin Binding Protein Phosphatase Binding Vascular Endothelial Growth Factor Receptor 2 Binding Transmembrane Transporter Binding Cadherin Binding Fibrinogen Binding BMP Receptor Binding Protein Tyrosine Kinase Binding
	Biological Process	Retina Homeostasis Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Visual Perception Response To Xenobiotic Stimulus Positive Regulation Of Gene Expression Positive Regulation Of Keratinocyte Proliferation Hair Cycle Process Keratinization Positive Regulation Of Tyrosinase Activity Negative Regulation Of Transforming Growth Factor Beta2 Production Wound Healing Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Melanin Biosynthetic Process Negative Regulation Of Timing Of Catagen Regulation Of Hair Cycle By Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Positive Regulation Of Melanosome Transport	Cell Morphogenesis Regulation Of Protein Phosphorylation Vasculature Development Blood Vessel Maturation Cellular Calcium Ion Homeostasis Cell-cell Junction Assembly Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Transforming Growth Factor Beta Receptor Signaling Pathway Multicellular Organism Development Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Cell Migration Positive Regulation Of BMP Signaling Pathway Negative Regulation Of Microtubule Polymerization Positive Regulation Of Protein-containing Complex Assembly Adherens Junction Organization Positive Regulation Of Protein Dephosphorylation Maintenance Of Blood-brain Barrier Regulation Of Vascular Permeability Blood Vessel Endothelial Cell Migration Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Bicellular Tight Junction Assembly Cell-cell Adhesion Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Protein Localization To Bicellular Tight Junction Positive Regulation Of Establishment Of Endothelial Barrier Regulation Of Establishment Of Cell Polarity Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways		Adherens junctions interactions	Adherens junctions interactions VEGFR2 mediated vascular permeability
Drugs			Lenalidomide FX06
Diseases
GWAS		Cutaneous melanoma or hair colour ( 32341527) Glycated hemoglobin levels ( 28898252) Mean reticulocyte volume ( 32888494) Multiple sclerosis ( 31604244 24076602) Platelet count ( 32888494) Red cell distribution width ( 27863252) Ulcerative colitis ( 28067908)	Body size at age 10 ( 32376654) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) High light scatter reticulocyte count ( 32888494) Iron status biomarkers (ferritin levels) ( 28334935) Lung function (FEV1/FVC) ( 30061609) Molar-incisor hypomineralization ( 23918034) Reticulocyte count ( 32888494)
Interacting Genes		4 interacting genes: CDH5 CTNNA1 CTNNB1 CTNND1	28 interacting genes: CA7 CDH1 CDH16 CDH3 CSK CTNNA1 CTNNB1 CTNND1 DSP EGFR EPHA2 F2RL2 FGA JUP KDR NQO1 P2RX4 P2RX6 PARD6A PKP4 PTPN11 PTPRB PYGB RND3 SHC1 SMG1 SRC VIM
Entrez ID		1001	1003
HPRD ID		00227	03075
Ensembl ID		ENSG00000062038	ENSG00000179776
Uniprot IDs		B4DLF0 P22223	P33151 Q59EA3
PDB IDs		4OY9 4ZML 4ZMN 4ZMO 4ZMP 4ZMQ 4ZMT 4ZMV 4ZMW 4ZMX 4ZMY 4ZMZ 5JYL 5JYM
Enriched GO Terms of Interacting Partners?
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