RBM39 and PRPF3

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		RBM39	PRPF3
Gene Name		RNA binding motif protein 39	pre-mRNA processing factor 3
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Microtubule Organizing Center Microtubule Cytoskeleton Nuclear Speck	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding	Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing MRNA Processing RNA Splicing	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		47 interactors: AK8 APP ARL6IP4 BANP C11orf57 CHERP CLK2 DDX39B ESR1 ESR2 FAM200A GOLGA2 HIST1H1C HNRNPH2 HOMEZ JUN KIAA0907 KRTAP12-2 MLX NCOA6 NKAP PGR PHC2 PPIG PRPF3 PRPF38A PRPF40A RBM23 RBM25 REL RNF113A RP9P SAP18 SAP30BP SDCBP SF3B4 SP100 SREK1IP1 SRPK1 SRPK2 SRSF11 THAP1 TOE1 TTC14 U2AF2 ZBTB22 ZCCHC10	24 interactors: BRCA1 CCDC85B CDC5L CTNNBL1 DPY30 DVL2 DVL3 FAM9B FRA10AC1 GTPBP3 NHP2L1 NKAP PCBP1 PPIH PRPF31 PRPF4 RBM39 SART3 SNIP1 TRIM39 U2AF2 USP4 WBP4 ZCCHC10
Entrez ID		9584	9129
HPRD ID		09201	07389
Ensembl ID		ENSG00000131051	ENSG00000117360
Uniprot IDs		B4DRA0 Q14498	E7EVD1 O43395
PDB IDs		2JRS	1X4Q
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression RNA Processing Nucleobase-containing Compound Metabolic Process MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Cellular Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process MRNA Splicing, Via Spliceosome Regulation Of Gene Expression RNA Splicing, Via Transesterification Reactions Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Intracellular Receptor Signaling Pathway Intracellular Estrogen Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Negative Regulation Of Viral Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Metabolic Process Regulation Of Metabolic Process Nucleocytoplasmic Transport Nuclear Transport Mammary Gland Branching Involved In Pregnancy Regulation Of Transcription, DNA-templated Regulation Of Viral Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Process MRNA Export From Nucleus Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Positive Regulation Of Viral Process Vagina Development RNA Export From Nucleus	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Spliceosomal Tri-snRNP Complex Assembly Cellular Metabolic Process Spliceosomal SnRNP Assembly Hematopoietic Stem Cell Proliferation Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Wnt Signaling Pathway, Planar Cell Polarity Pathway Ribonucleoprotein Complex Biogenesis Metabolic Process Cochlea Morphogenesis Regulation Of Gene Expression Non-canonical Wnt Signaling Pathway Ribonucleoprotein Complex Assembly Regulation Of Protein Ubiquitination Cochlea Development Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone Deubiquitination Positive Regulation Of Histone H4-K16 Acetylation Outflow Tract Morphogenesis Positive Regulation Of Histone Modification Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of JUN Kinase Activity Cellular Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of JUN Kinase Activity Stem Cell Proliferation Convergent Extension Involved In Neural Plate Elongation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Signal Transduction In Response To DNA Damage RNA Biosynthetic Process Canonical Wnt Signaling Pathway Regulation Of Metabolic Process Inner Ear Morphogenesis Negative Regulation Of Protein Ubiquitination Non-canonical Wnt Signaling Pathway Via JNK Cascade
Tagcloud ?			accumulative assumes debilitating decades degeneration developmentally example focused hypotheses hypothesis implying interacting interrupt intriguing metabolically methodology mildly phenomenon photoreceptors principal prp31 prpc8 retina retinal rp18 snrnas splicing suboptimal ubiquitously
Tagcloud (Difference) ?			accumulative assumes debilitating decades degeneration developmentally example focused hypotheses hypothesis implying interacting interrupt intriguing metabolically methodology mildly phenomenon photoreceptors principal prp31 prpc8 retina retinal rp18 snrnas splicing suboptimal ubiquitously
Tagcloud (Intersection) ?