PRPF3 and NHP2L1

Number of citations of the paper that reports this interaction (PMID 16723661)
44

Data Source:
BioGRID (two hybrid)

		PRPF3	NHP2L1
Gene Name		pre-mRNA processing factor 3	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Box C/D SnoRNP Complex Protein Complex
	Molecular Function	Protein Binding Identical Protein Binding Poly(A) RNA Binding	RNA Binding Protein Binding SnoRNA Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression Ribosome Biogenesis
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: BRCA1 CCDC85B CDC5L CTNNBL1 DPY30 DVL2 DVL3 FAM9B FRA10AC1 GTPBP3 NHP2L1 NKAP PCBP1 PPIH PRPF31 PRPF4 RBM39 SART3 SNIP1 TRIM39 U2AF2 USP4 WBP4 ZCCHC10	14 interactors: CDKN2C CHST1 GTF3C1 LRIF1 MAP1LC3B POLA2 PPIH PRPF3 PRPF31 PRPF4 RAD17 RBM10 SNW1 XRCC6
Entrez ID		9129	4809
HPRD ID		07389	03197
Ensembl ID		ENSG00000117360	ENSG00000100138
Uniprot IDs		E7EVD1 O43395	P55769 Q6FHM6
PDB IDs		1X4Q	1E7K 2JNB 2OZB 3SIU 3SIV
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Spliceosomal Tri-snRNP Complex Assembly Cellular Metabolic Process Spliceosomal SnRNP Assembly Hematopoietic Stem Cell Proliferation Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Wnt Signaling Pathway, Planar Cell Polarity Pathway Ribonucleoprotein Complex Biogenesis Metabolic Process Cochlea Morphogenesis Regulation Of Gene Expression Non-canonical Wnt Signaling Pathway Ribonucleoprotein Complex Assembly Regulation Of Protein Ubiquitination Cochlea Development Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone Deubiquitination Positive Regulation Of Histone H4-K16 Acetylation Outflow Tract Morphogenesis Positive Regulation Of Histone Modification Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of JUN Kinase Activity Cellular Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of JUN Kinase Activity Stem Cell Proliferation Convergent Extension Involved In Neural Plate Elongation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Signal Transduction In Response To DNA Damage RNA Biosynthetic Process Canonical Wnt Signaling Pathway Regulation Of Metabolic Process Inner Ear Morphogenesis Negative Regulation Of Protein Ubiquitination Non-canonical Wnt Signaling Pathway Via JNK Cascade	RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Spliceosomal Tri-snRNP Complex Assembly RNA Metabolic Process Gene Expression Cellular Metabolic Process Spliceosomal SnRNP Assembly Positive Regulation Of Viral Process Telomere Maintenance Positive Regulation Of Vitamin D Receptor Signaling Pathway Cellular Hyperosmotic Salinity Response Macromolecule Biosynthetic Process 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Cellular Response To X-ray Regulation Of Vitamin D Receptor Signaling Pathway Regulation Of Viral Process G1/S Transition Of Mitotic Cell Cycle TRNA Transcription Ribonucleoprotein Complex Assembly Establishment Of Integrated Proviral Latency Metabolic Process Cellular Hyperosmotic Response Hyperosmotic Salinity Response Establishment Of Viral Latency Positive Regulation By Host Of Viral Transcription Mitotic Cell Cycle Process DNA Replication Checkpoint Cellular Response To Salt Stress DNA Recombination Mitotic Cell Cycle DNA Ligation
Tagcloud ?		accumulative assumes debilitating decades degeneration developmentally example focused hypotheses hypothesis implying interacting interrupt intriguing metabolically methodology mildly phenomenon photoreceptors principal prp31 prpc8 retina retinal rp18 snrnas splicing suboptimal ubiquitously
Tagcloud (Difference) ?		accumulative assumes debilitating decades degeneration developmentally example focused hypotheses hypothesis implying interacting interrupt intriguing metabolically methodology mildly phenomenon photoreceptors principal prp31 prpc8 retina retinal rp18 snrnas splicing suboptimal ubiquitously
Tagcloud (Intersection) ?