RBM39 and MLX

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RBM39	MLX
Gene Name		RNA binding motif protein 39	MLX, MAX dimerization protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Microtubule Organizing Center Microtubule Cytoskeleton Nuclear Speck	Nucleus Cytoplasm
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing MRNA Processing RNA Splicing	Negative Regulation Of Transcription From RNA Polymerase II Promoter Energy Reserve Metabolic Process Transcription, DNA-templated Regulation Of Transcription, DNA-templated Nucleocytoplasmic Transport Positive Regulation Of Cellular Metabolic Process Small Molecule Metabolic Process Negative Regulation Of Transcription, DNA-templated
Pathways			Integration of energy metabolism ChREBP activates metabolic gene expression
Drugs
Diseases
GWAS			Crohn's disease ( 21102463)
Protein-Protein Interactions		47 interactors: AK8 APP ARL6IP4 BANP C11orf57 CHERP CLK2 DDX39B ESR1 ESR2 FAM200A GOLGA2 HIST1H1C HNRNPH2 HOMEZ JUN KIAA0907 KRTAP12-2 MLX NCOA6 NKAP PGR PHC2 PPIG PRPF3 PRPF38A PRPF40A RBM23 RBM25 REL RNF113A RP9P SAP18 SAP30BP SDCBP SF3B4 SP100 SREK1IP1 SRPK1 SRPK2 SRSF11 THAP1 TOE1 TTC14 U2AF2 ZBTB22 ZCCHC10	13 interactors: AES APP GABARAPL2 ID3 MAD1L1 MLXIP MLXIPL MNT MXD1 MXD4 RBM39 SAP30BP ZBTB32
Entrez ID		9584	6945
HPRD ID		09201	04278
Ensembl ID		ENSG00000131051	ENSG00000108788
Uniprot IDs		B4DRA0 Q14498	Q9UH92
PDB IDs		2JRS
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression RNA Processing Nucleobase-containing Compound Metabolic Process MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Cellular Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process MRNA Splicing, Via Spliceosome Regulation Of Gene Expression RNA Splicing, Via Transesterification Reactions Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Intracellular Receptor Signaling Pathway Intracellular Estrogen Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Negative Regulation Of Viral Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Metabolic Process Regulation Of Metabolic Process Nucleocytoplasmic Transport Nuclear Transport Mammary Gland Branching Involved In Pregnancy Regulation Of Transcription, DNA-templated Regulation Of Viral Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Process MRNA Export From Nucleus Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Positive Regulation Of Viral Process Vagina Development RNA Export From Nucleus	Negative Regulation Of Cellular Metabolic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Macromolecule Biosynthetic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Cell Cycle Regulation Of Cellular Process Cellular Metabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Carbohydrate Metabolic Process By Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metaphase Plate Congression Glucose Mediated Signaling Pathway Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Negative Regulation Of Protein Metabolic Process Synaptic Growth At Neuromuscular Junction Regulation Of Protein Processing Carbohydrate Mediated Signaling Collateral Sprouting In Absence Of Injury Negative Regulation Of Protein Catabolic Process Regulation Of Cell Cycle Process Negative Regulation Of Oxidative Phosphorylation Positive Regulation Of Anoikis Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Protein Binding
Tagcloud ?			accumulate acetyltransferase adapt bhlhzip circuitry defective fitness fundamental glucose helix homeostasis intracellular leucine mechanistic mondoa next occupancy organismal requirement respond sense simply steps stimulate stimulates transcriptionally trigger underlies zipper
Tagcloud (Difference) ?			accumulate acetyltransferase adapt bhlhzip circuitry defective fitness fundamental glucose helix homeostasis intracellular leucine mechanistic mondoa next occupancy organismal requirement respond sense simply steps stimulate stimulates transcriptionally trigger underlies zipper
Tagcloud (Intersection) ?