HOMER1 and DNM3

Number of citations of the paper that reports this interaction (PMID 9808459)
116

Data Source:
HPRD (in vitro)

		HOMER1	DNM3
Gene Name		homer homolog 1 (Drosophila)	dynamin 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Z Disc Cell Junction Axon Neuronal Cell Body Costamere Dendritic Shaft Apical Part Of Cell Postsynaptic Membrane Excitatory Synapse Neuronal Postsynaptic Density	Mitochondrion Microtubule Postsynaptic Density Dendritic Spine Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Type 5 Metabotropic Glutamate Receptor Binding Protein Complex Scaffold G-protein Coupled Glutamate Receptor Binding Signaling Adaptor Activity Identical Protein Binding Ion Channel Binding Protein Heterodimerization Activity Scaffold Protein Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Skeletal Muscle Contraction Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway Synaptic Transmission Circadian Rhythm Positive Regulation Of Signal Transduction Response To Nicotine Protein Localization To Synapse Behavioral Response To Cocaine Skeletal Muscle Fiber Development Chemical Homeostasis Within A Tissue Response To Calcium Ion Positive Regulation Of Calcium Ion Transport Regulation Of Calcium Ion Import Regulation Of Store-operated Calcium Entry Regulation Of Cation Channel Activity	Endocytosis Synapse Assembly Metabolic Process Filopodium Assembly
Pathways			Retrograde neurotrophin signalling Signalling by NGF Axon guidance L1CAM interactions NGF signalling via TRKA from the plasma membrane Recycling pathway of L1 Toll-Like Receptors Cascades Toll Like Receptor 4 (TLR4) Cascade MHC class II antigen presentation Adaptive Immune System Innate Immune System
Drugs
Diseases
GWAS		Height ( 18193045) Major depressive disorder ( 20673876)	Bone mineral density ( 22504420) Height ( 20881960 23563607 18391951) Mean platelet volume ( 22139419 19820697) Platelet counts ( 22139419) Waist-hip ratio ( 20935629)
Protein-Protein Interactions		19 interactors: ABI3 AGAP2 C19orf57 C1orf116 DNM3 EFNB2 FAT1 GRIA1 GRIK1 GRM1 GRM5 HOMER3 ITPR1 RYR1 RYR2 SHANK1 STX12 TANC1 TRPC1	2 interactors: DYNLL1 HOMER1
Entrez ID		9456	26052
HPRD ID		09211	13241
Ensembl ID			ENSG00000197959
Uniprot IDs		Q5U5K4 Q86YM7	Q6P2G1 Q9UQ16
PDB IDs			3L43
Enriched GO Terms of Interacting Partners?		Glutamate Receptor Signaling Pathway Cell-cell Signaling Cytosolic Calcium Ion Homeostasis G-protein Coupled Glutamate Receptor Signaling Pathway Cellular Calcium Ion Homeostasis Release Of Sequestered Calcium Ion Into Cytosol Calcium Ion Homeostasis Regulation Of Sequestering Of Calcium Ion Behavior Regulation Of Ion Transport Calcium Ion Transport Into Cytosol Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Transport Regulation Of Ion Homeostasis Cellular Metal Ion Homeostasis Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Synaptic Transmission, Glutamatergic Cellular Cation Homeostasis Calcium Ion Transmembrane Transport Cellular Ion Homeostasis Single-organism Behavior Metal Ion Homeostasis Developmental Process Sarcoplasmic Reticulum Calcium Ion Transport Cellular Response To Caffeine Cellular Chemical Homeostasis Learning Or Memory Ion Homeostasis Cognition Synaptic Transmission Regulation Of Synaptic Transmission Calcium Ion Transport Dendritic Spine Organization Cellular Homeostasis Learning Cell Projection Organization Response To Caffeine Multicellular Organismal Development Anatomical Structure Morphogenesis Ion Transmembrane Transport Anatomical Structure Development Chemical Homeostasis Regulation Of Calcium Ion Transport Ionotropic Glutamate Receptor Signaling Pathway Cellular Response To Alkaloid Positive Regulation Of Ion Transport Synaptic Transmission, Glutamatergic Long-term Memory Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Determination Of Affect	Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway Positive Regulation Of Transport Chemical Homeostasis Within A Tissue Behavioral Response To Cocaine Regulation Of Store-operated Calcium Entry G-protein Coupled Glutamate Receptor Signaling Pathway Protein Localization To Synapse Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Calcium Ion Import Skeletal Muscle Fiber Development Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Skeletal Muscle Contraction Myotube Cell Development Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Signal Transduction Substantia Nigra Development Response To Nicotine Musculoskeletal Movement Muscle Fiber Development Response To Cocaine Neural Nucleus Development Positive Regulation Of Mitochondrion Organization Myotube Differentiation Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Glutamate Receptor Signaling Pathway Regulation Of Cation Channel Activity Striated Muscle Contraction Midbrain Development Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Positive Regulation Of Calcium Ion Transport Response To Ammonium Ion Regulation Of Mitochondrion Organization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Female Gamete Generation Response To Calcium Ion G2/M Transition Of Mitotic Cell Cycle Skeletal Muscle Tissue Development Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Response To Alkaloid Skeletal Muscle Organ Development Striated Muscle Cell Development Regulation Of Signal Transduction Adult Behavior Muscle Cell Development Circadian Rhythm
Tagcloud ?		accumbens brn2 decondensed dmnt1 dnmt3a erg1 exceptionally fox3 foxg1 gadd45a gadd45b hdac11 kat2b kat3a kat3b kat5 multilineage multipotent nef1 neg neun neurobiol neurobiology neuroplasticity nfl nuclei periodicals pons syt1	1q24 200k aaa adventitial aneurysm aortic atherosclerosis atherosclerotic c1orf105 carotid cimt cohorts compensatory determinants enlargement expansive forward iccad illumina intima metabochip pigc pooling proxy q remodelling rs3768445 rs4916251 snp
Tagcloud (Difference) ?		accumbens brn2 decondensed dmnt1 dnmt3a erg1 exceptionally fox3 foxg1 gadd45a gadd45b hdac11 kat2b kat3a kat3b kat5 multilineage multipotent nef1 neg neun neurobiol neurobiology neuroplasticity nfl nuclei periodicals pons syt1	1q24 200k aaa adventitial aneurysm aortic atherosclerosis atherosclerotic c1orf105 carotid cimt cohorts compensatory determinants enlargement expansive forward iccad illumina intima metabochip pigc pooling proxy q remodelling rs3768445 rs4916251 snp
Tagcloud (Intersection) ?