DNM3

Gene Name		dynamin 3
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Gene Ontology Annotations	Cellular Component	Mitochondrion Microtubule Postsynaptic Density Dendritic Spine Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding
	Biological Process	Endocytosis Synapse Assembly Metabolic Process Filopodium Assembly
Pathways		Retrograde neurotrophin signalling Signalling by NGF Axon guidance L1CAM interactions NGF signalling via TRKA from the plasma membrane Recycling pathway of L1 Toll-Like Receptors Cascades Toll Like Receptor 4 (TLR4) Cascade MHC class II antigen presentation Adaptive Immune System Innate Immune System
Drugs
Diseases
GWAS		Bone mineral density ( 22504420) Height ( 20881960 23563607 18391951) Mean platelet volume ( 22139419 19820697) Platelet counts ( 22139419) Waist-hip ratio ( 20935629)
Protein-protein Interactions		2 interactors: DYNLL1 HOMER1
Entrez ID		26052
HPRD ID		13241
Ensembl ID		ENSG00000197959
Uniprot IDs		Q6P2G1 Q9UQ16
PDB IDs		3L43
Enriched GO Terms of Interacting Partners?		Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway Positive Regulation Of Transport Chemical Homeostasis Within A Tissue Behavioral Response To Cocaine Regulation Of Store-operated Calcium Entry G-protein Coupled Glutamate Receptor Signaling Pathway Protein Localization To Synapse Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Calcium Ion Import Skeletal Muscle Fiber Development Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Skeletal Muscle Contraction Myotube Cell Development Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Signal Transduction Substantia Nigra Development Response To Nicotine Musculoskeletal Movement Muscle Fiber Development Response To Cocaine Neural Nucleus Development Positive Regulation Of Mitochondrion Organization Myotube Differentiation Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Glutamate Receptor Signaling Pathway Regulation Of Cation Channel Activity Striated Muscle Contraction Midbrain Development Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Positive Regulation Of Calcium Ion Transport Response To Ammonium Ion Regulation Of Mitochondrion Organization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Female Gamete Generation Response To Calcium Ion G2/M Transition Of Mitotic Cell Cycle Skeletal Muscle Tissue Development Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Response To Alkaloid Skeletal Muscle Organ Development Striated Muscle Cell Development Regulation Of Signal Transduction Adult Behavior Muscle Cell Development Circadian Rhythm
Tagcloud ?		1q24 200k aaa adventitial aneurysm aortic atherosclerosis atherosclerotic c1orf105 carotid cimt cohorts compensatory determinants enlargement expansive forward iccad illumina intima metabochip pigc pooling proxy q remodelling rs3768445 rs4916251 snp