HOMER1 and FAT1

Number of citations of the paper that reports this interaction (PMID 16979624)
4

Data Source:
HPRD (in vitro)

		HOMER1	FAT1
Gene Name		homer homolog 1 (Drosophila)	FAT atypical cadherin 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Z Disc Cell Junction Axon Neuronal Cell Body Costamere Dendritic Shaft Apical Part Of Cell Postsynaptic Membrane Excitatory Synapse Neuronal Postsynaptic Density	Nucleus Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Lamellipodium Filopodium Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Type 5 Metabotropic Glutamate Receptor Binding Protein Complex Scaffold G-protein Coupled Glutamate Receptor Binding Signaling Adaptor Activity Identical Protein Binding Ion Channel Binding Protein Heterodimerization Activity Scaffold Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Skeletal Muscle Contraction Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway Synaptic Transmission Circadian Rhythm Positive Regulation Of Signal Transduction Response To Nicotine Protein Localization To Synapse Behavioral Response To Cocaine Skeletal Muscle Fiber Development Chemical Homeostasis Within A Tissue Response To Calcium Ion Positive Regulation Of Calcium Ion Transport Regulation Of Calcium Ion Import Regulation Of Store-operated Calcium Entry Regulation Of Cation Channel Activity	Actin Filament Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Establishment Or Maintenance Of Cell Polarity Cell-cell Signaling Anatomical Structure Morphogenesis Single Organismal Cell-cell Adhesion Cell Migration
Pathways
Drugs
Diseases
GWAS		Height ( 18193045) Major depressive disorder ( 20673876)	Obesity ( 21552555)
Protein-Protein Interactions		19 interactors: ABI3 AGAP2 C19orf57 C1orf116 DNM3 EFNB2 FAT1 GRIA1 GRIK1 GRM1 GRM5 HOMER3 ITPR1 RYR1 RYR2 SHANK1 STX12 TANC1 TRPC1	4 interactors: ENAH HOMER1 HOMER3 VASP
Entrez ID		9456	2195
HPRD ID		09211	02986
Ensembl ID			ENSG00000083857
Uniprot IDs		Q5U5K4 Q86YM7	Q14517
PDB IDs
Enriched GO Terms of Interacting Partners?		Glutamate Receptor Signaling Pathway Cell-cell Signaling Cytosolic Calcium Ion Homeostasis G-protein Coupled Glutamate Receptor Signaling Pathway Cellular Calcium Ion Homeostasis Release Of Sequestered Calcium Ion Into Cytosol Calcium Ion Homeostasis Regulation Of Sequestering Of Calcium Ion Behavior Regulation Of Ion Transport Calcium Ion Transport Into Cytosol Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Transport Regulation Of Ion Homeostasis Cellular Metal Ion Homeostasis Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Synaptic Transmission, Glutamatergic Cellular Cation Homeostasis Calcium Ion Transmembrane Transport Cellular Ion Homeostasis Single-organism Behavior Metal Ion Homeostasis Developmental Process Sarcoplasmic Reticulum Calcium Ion Transport Cellular Response To Caffeine Cellular Chemical Homeostasis Learning Or Memory Ion Homeostasis Cognition Synaptic Transmission Regulation Of Synaptic Transmission Calcium Ion Transport Dendritic Spine Organization Cellular Homeostasis Learning Cell Projection Organization Response To Caffeine Multicellular Organismal Development Anatomical Structure Morphogenesis Ion Transmembrane Transport Anatomical Structure Development Chemical Homeostasis Regulation Of Calcium Ion Transport Ionotropic Glutamate Receptor Signaling Pathway Cellular Response To Alkaloid Positive Regulation Of Ion Transport Synaptic Transmission, Glutamatergic Long-term Memory Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Determination Of Affect	Regulation Of Store-operated Calcium Entry G-protein Coupled Glutamate Receptor Signaling Pathway Glutamate Receptor Signaling Pathway Actin Polymerization Or Depolymerization Neural Tube Closure T Cell Receptor Signaling Pathway Neural Tube Formation Antigen Receptor-mediated Signaling Pathway Embryonic Epithelial Tube Formation Epithelial Tube Formation Tube Formation Morphogenesis Of Embryonic Epithelium Cell Surface Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway Regulation Of Calcium Ion Transport Neural Tube Development Immune Response-activating Cell Surface Receptor Signaling Pathway Actin Filament Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Tissue Development Epithelial Tube Morphogenesis Axon Guidance Cell Development Tube Morphogenesis Chemical Homeostasis Within A Tissue Immune Response-regulating Signaling Pathway Behavioral Response To Cocaine Signal Transduction Morphogenesis Of An Epithelium Axonogenesis Protein Localization To Synapse Signaling Axon Development Cell Communication Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Actin Cytoskeleton Organization Regulation Of Calcium Ion Import Skeletal Muscle Fiber Development Regulation Of Ion Transport Positive Regulation Of Immune Response Neuron Projection Morphogenesis Actin Filament-based Process Embryonic Morphogenesis Tissue Morphogenesis Skeletal Muscle Contraction Myotube Cell Development Tube Development Cell Morphogenesis Involved In Differentiation Cellular Response To Stimulus
Tagcloud ?		accumbens brn2 decondensed dmnt1 dnmt3a erg1 exceptionally fox3 foxg1 gadd45a gadd45b hdac11 kat2b kat3a kat3b kat5 multilineage multipotent nef1 neg neun neurobiol neurobiology neuroplasticity nfl nuclei periodicals pons syt1	bcl11b cadherin discovered dnm2 druggable exhibitedthe fbxw7 frequencies guide harboured herc1 jak jak3 lymphoblastic mll2 mutational notch1 notch2 phf6 recurrent regulators reln secretase splicing subclonal unfavourable warranted wt1 zrsr2
Tagcloud (Difference) ?		accumbens brn2 decondensed dmnt1 dnmt3a erg1 exceptionally fox3 foxg1 gadd45a gadd45b hdac11 kat2b kat3a kat3b kat5 multilineage multipotent nef1 neg neun neurobiol neurobiology neuroplasticity nfl nuclei periodicals pons syt1	bcl11b cadherin discovered dnm2 druggable exhibitedthe fbxw7 frequencies guide harboured herc1 jak jak3 lymphoblastic mll2 mutational notch1 notch2 phf6 recurrent regulators reln secretase splicing subclonal unfavourable warranted wt1 zrsr2
Tagcloud (Intersection) ?