FAT1 and HOMER3

Number of citations of the paper that reports this interaction (PMID 16979624)
4

Data Source:
HPRD (in vitro)

		FAT1	HOMER3
Gene Name		FAT atypical cadherin 1	homer homolog 3 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Lamellipodium Filopodium Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Cellular_component Cytoplasm Cytosol Plasma Membrane Cell Junction Basal Part Of Cell Postsynaptic Membrane Neuronal Postsynaptic Density
	Molecular Function	Calcium Ion Binding Protein Binding	Protein Binding Protein C-terminus Binding Protein Domain Specific Binding G-protein Coupled Glutamate Receptor Binding
	Biological Process	Actin Filament Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Establishment Or Maintenance Of Cell Polarity Cell-cell Signaling Anatomical Structure Morphogenesis Single Organismal Cell-cell Adhesion Cell Migration	Protein Targeting G-protein Coupled Glutamate Receptor Signaling Pathway Regulation Of Store-operated Calcium Entry
Pathways
Drugs
Diseases
GWAS		Obesity ( 21552555)
Protein-Protein Interactions		4 interactors: ENAH HOMER1 HOMER3 VASP	28 interactors: ABI2 ABI3 APP CEBPB DYNLL2 EAF1 EIF3D FAT1 FRYL GRM5 HOMER1 ITPR1 MOS NEBL PAX6 PKN1 POM121 PPP1R18 PSMA1 PSMA2 PSMC5 RUNX1T1 RYR1 SNRPF SRPK2 TRPC1 USP2 WIPF1
Entrez ID		2195	9454
HPRD ID		02986	07270
Ensembl ID		ENSG00000083857	ENSG00000051128
Uniprot IDs		Q14517	B2RA10 Q9NSC5
PDB IDs			2P8V 3CVF
Enriched GO Terms of Interacting Partners?		Regulation Of Store-operated Calcium Entry G-protein Coupled Glutamate Receptor Signaling Pathway Glutamate Receptor Signaling Pathway Actin Polymerization Or Depolymerization Neural Tube Closure T Cell Receptor Signaling Pathway Neural Tube Formation Antigen Receptor-mediated Signaling Pathway Embryonic Epithelial Tube Formation Epithelial Tube Formation Tube Formation Morphogenesis Of Embryonic Epithelium Cell Surface Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway Regulation Of Calcium Ion Transport Neural Tube Development Immune Response-activating Cell Surface Receptor Signaling Pathway Actin Filament Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Tissue Development Epithelial Tube Morphogenesis Axon Guidance Cell Development Tube Morphogenesis Chemical Homeostasis Within A Tissue Immune Response-regulating Signaling Pathway Behavioral Response To Cocaine Signal Transduction Morphogenesis Of An Epithelium Axonogenesis Protein Localization To Synapse Signaling Axon Development Cell Communication Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Actin Cytoskeleton Organization Regulation Of Calcium Ion Import Skeletal Muscle Fiber Development Regulation Of Ion Transport Positive Regulation Of Immune Response Neuron Projection Morphogenesis Actin Filament-based Process Embryonic Morphogenesis Tissue Morphogenesis Skeletal Muscle Contraction Myotube Cell Development Tube Development Cell Morphogenesis Involved In Differentiation Cellular Response To Stimulus	Positive Regulation Of Cell Cycle Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway Gene Expression Regulation Of Cell Cycle Phase Transition Regulation Of Protein Metabolic Process Regulation Of Cellular Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Glutamate Receptor Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Cycle Signaling Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Regulation Of Mitotic Cell Cycle Positive Regulation Of Ligase Activity Cell Communication DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To Stimulus Antigen Processing And Presentation Of Peptide Antigen Intracellular Signal Transduction Response To Stimulus Signal Transduction Single-organism Behavior Cell Differentiation Regulation Of Ubiquitin-protein Transferase Activity Movement Of Cell Or Subcellular Component Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction In Response To DNA Damage Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Mitotic DNA Damage Checkpoint Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Process Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Arrest
Tagcloud ?		bcl11b cadherin discovered dnm2 druggable exhibitedthe fbxw7 frequencies guide harboured herc1 jak jak3 lymphoblastic mll2 mutational notch1 notch2 phf6 recurrent regulators reln secretase splicing subclonal unfavourable warranted wt1 zrsr2	abetapp alzheimer analyzing assembly coil coiled deposition derivative emphasis evh1 generation herein importantly interacting interaction interacts manipulate metabolism offer plaques players polymerization possibly seems senile serine tail
Tagcloud (Difference) ?		bcl11b cadherin discovered dnm2 druggable exhibitedthe fbxw7 frequencies guide harboured herc1 jak jak3 lymphoblastic mll2 mutational notch1 notch2 phf6 recurrent regulators reln secretase splicing subclonal unfavourable warranted wt1 zrsr2	abetapp alzheimer analyzing assembly coil coiled deposition derivative emphasis evh1 generation herein importantly interacting interaction interacts manipulate metabolism offer plaques players polymerization possibly seems senile serine tail
Tagcloud (Intersection) ?