FAM58A and PTPN5

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		FAM58A	PTPN5
Gene Name		family with sequence similarity 58, member A	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	DNA-directed RNA Polymerase II, Holoenzyme	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Kinase Binding Protein Kinase Activator Activity	Phosphotyrosine Binding Protein Tyrosine Phosphatase Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Transcription, DNA-templated Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Kinase Activity	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS		Type 2 diabetes ( 22961080)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065)
Protein-Protein Interactions		1 interactors: PTPN5	11 interactors: CUL5 CXCL9 FAM58A FYN MAPK1 MAPK3 SNX4 TERF1 TMEM51 VTI1B ZBTB5
Entrez ID		92002	84867
HPRD ID		06645	01472
Ensembl ID		ENSG00000147382	ENSG00000110786
Uniprot IDs		Q8N1B3	B7Z2F8 B7ZAF5 P54829 Q86TL3
PDB IDs			2BIJ 2BV5 2CJZ
Enriched GO Terms of Interacting Partners?			Regulation Of Golgi Inheritance Caveolin-mediated Endocytosis Regulation Of Cellular Localization Regulation Of Golgi Organization Sensory Perception Of Pain Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Early Endosome To Late Endosome Transport Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Immune System Process Regulation Of Intracellular Transport Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Cellular Response To Fibroblast Growth Factor Stimulus Response To Epidermal Growth Factor Viral Process Platelet Activation Response To Fibroblast Growth Factor Regulation Of Cellular Response To Heat Regulation Of Cellular Component Organization Neurotrophin TRK Receptor Signaling Pathway Chemotaxis Lipopolysaccharide-mediated Signaling Pathway Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Signal Transduction Positive Regulation Of Immune Response Response To Growth Hormone Regulation Of Immune System Process Phagocytosis Response To Exogenous DsRNA Fc Receptor Signaling Pathway Cell Proliferation Immune Response-activating Cell Surface Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway JAK-STAT Cascade Vesicle-mediated Transport Toll-like Receptor 10 Signaling Pathway Cellular Response To Peptide Hormone Stimulus Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Response To Lipopolysaccharide Toll-like Receptor 2 Signaling Pathway
Tagcloud ?			ad aggregated aggregates amyloid beneficial biology burden called discovery disrupts economic enriched hyperphosphorylated making millions modulating neurofibrillary neuropathology nfts plaques representing reviews step striatal substantial tangles trafficking turn worldwide
Tagcloud (Difference) ?			ad aggregated aggregates amyloid beneficial biology burden called discovery disrupts economic enriched hyperphosphorylated making millions modulating neurofibrillary neuropathology nfts plaques representing reviews step striatal substantial tangles trafficking turn worldwide
Tagcloud (Intersection) ?